Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.45 |
| ▸ | XIAP | P98170 | 5/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29048164 | 0.82 | SMN1; SMN2 (0.57) | NPY1RKMT2AL3MBTL1SCN9A | |
| SCHEMBL18870010 | 0.81 | ALDH1A1 (0.51) | NPY1RKMT2AL3MBTL1SCN9AXIAP | |
| SCHEMBL29270735 | 0.80 | SRC (0.50) | NPY1RKMT2AL3MBTL1XIAP | |
| SCHEMBL18870009 | 0.79 | SCN9A (0.45) | NPY1RKMT2AL3MBTL1SCN9A | |
| SCHEMBL30767659 | 0.77 | XIAP (0.43) | NPY1RKMT2AL3MBTL1SCN9AXIAP | |
| SCHEMBL26961658 | 0.76 | XIAP (0.46) | NPY1RXIAP | |
| SCHEMBL29796998 | 0.76 | XIAP (0.46) | NPY1RXIAP | |
| SCHEMBL6159504 | 0.76 | HCRTR1 (0.49) | KMT2AHCRTR1HCRTR2 | |
| SCHEMBL30767691 | 0.75 | NPY1R (0.40) | NPY1RKMT2AL3MBTL1SCN9AXIAP | |
| SCHEMBL6818187 | 0.75 | GAA (0.50) | NPY1RKMT2AL3MBTL1SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6953789-B2 | Thiol compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2005-10-11 | — | — | US | disclosed |
| US-20040157894-A1 | Thiol compounds, their production and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-08-12 | — | — | US | disclosed |
| US-6699881-B2 | MATRIX METALLOPROTEASE INHIBITORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2004-03-02 | — | — | US | disclosed |
| US-20030078253-A1 | Thiol compounds, their production and use | TAKEDA PHARMACEUTICAL COMPANY, LIMITED (JP) | 2003-04-24 | — | — | US | disclosed |
| US-6420415-B1 | Thiol compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-07-16 | — | — | US | disclosed |
| EP-1132379-A1 | NOVEL THIOL DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND UTILIZATION THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2001-09-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030078253-A1 | Thiol compounds, their production and use | TST, QSOX1, SULT1E1 | NPY1R 1600/4885KMT2A 1898/4885L3MBTL1 3315/4885 |
| US-20040157894-A1 | Thiol compounds, their production and use | TST, SULT1E1, QSOX1 | NPY1R 1521/4885KMT2A 1850/4885L3MBTL1 3278/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.