Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | RECQL | P46063 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6161094 | 1.00 | LMNA (0.36) | LMNAMAPTMAPK1GPR84ALDH1A1 | |
| SCHEMBL6159934 | 0.88 | GPR84 (0.31) | GPR84 | |
| SCHEMBL6162360 | 0.78 | HPGD (0.33) | MAPTALDH1A1 | |
| SCHEMBL6966214 | 0.77 | — | — | |
| SCHEMBL6161865 | 0.74 | NPC1 (0.30) | — | |
| SCHEMBL6160630 | 0.74 | NPC1 (0.30) | — | |
| SCHEMBL7079384 | 0.73 | — | — | |
| SCHEMBL6162089 | 0.72 | LMNA (0.36) | LMNAMAPTMAPK1ALDH1A1GAA | |
| SCHEMBL7080940 | 0.72 | MEN1 (0.31) | LMNAMAPTALDH1A1 | |
| SCHEMBL3453582 | 0.72 | CDC7 (0.32) | LMNAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0893442-B1 | LYMPH-ABSORBABLE IMIDAZOLE DERIVATIVES | SHIONOGI & CO (JP) | 2005-01-12 | — | — | EP | disclosed |
| US-6054591-A | LYMPHOTROPIC ANTI-AIDS AGENT | SHIONOGI & CO., LTD. (JP) | 2000-04-25 | — | — | US | disclosed |
| EP-0893442-A1 | LYMPH-ABSORBABLE IMIDAZOLE DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 1999-01-27 | — | — | EP | disclosed |