Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA1 | Q09470 | 5/20 | 0.55 |
| ▸ | KCNAB1 | Q14722 | 5/20 | 0.55 |
| ▸ | GHSR | Q92847 | 9/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6160934 | 1.00 | KCNA1 (0.55) | KCNA1KCNAB1GHSRMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6160605 | 0.99 | KCNA1 (0.55) | KCNA1KCNAB1GHSRMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6160591 | 0.99 | KCNA1 (0.55) | KCNA1KCNAB1GHSRMEN1KMT2A | |
| SCHEMBL6162216 | 0.89 | KCNA1 (0.48) | KCNA1KCNAB1GHSRMEN1KMT2A | |
| SCHEMBL6160450 | 0.88 | KCNA1 (0.52) | KCNA1KCNAB1KMT2A | |
| SCHEMBL6160463 | 0.88 | KCNA1 (0.52) | KCNA1KCNAB1KMT2A | |
| Hydrochloric Acid SCHEMBL6161668 | 0.87 | KCNA1 (0.51) | KCNA1KCNAB1KMT2A | |
| Hydrochloric Acid SCHEMBL6161323 | 0.87 | KCNA1 (0.51) | KCNA1KCNAB1KMT2A | |
| SCHEMBL6160785 | 0.85 | GHSR (0.52) | GHSRKMT2ACYP3A4 | |
| SCHEMBL6160779 | 0.85 | GHSR (0.52) | GHSRKMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | claimed |
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | disclosed |
| EP-0828754-A1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER INC. (US) | 1998-03-18 | — | — | EP | disclosed |
| WO-1996038471-A1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER INC. (US) | 1996-12-05 | — | — | WO | disclosed |