Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA1 | Q09470 | 4/20 | 0.48 |
| ▸ | KCNAB1 | Q14722 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.41 |
| ▸ | GHSR | Q92847 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | UGCG | Q16739 | 1/20 | 0.38 |
| ▸ | CCKBR | P32239 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6164155 | 0.89 | P2RX7 (0.49) | KCNA1KCNAB1P2RX7HCRTR2 | |
| SCHEMBL6160934 | 0.89 | KCNA1 (0.55) | KCNA1KCNAB1MEN1KMT2AGHSR | |
| SCHEMBL6160943 | 0.89 | KCNA1 (0.55) | KCNA1KCNAB1MEN1KMT2AGHSR | |
| Hydrochloric Acid SCHEMBL6160591 | 0.88 | KCNA1 (0.55) | KCNA1KCNAB1MEN1KMT2AGHSR | |
| Hydrochloric Acid SCHEMBL6160605 | 0.88 | KCNA1 (0.55) | KCNA1KCNAB1MEN1KMT2AGHSR | |
| SCHEMBL6162496 | 0.87 | PPARA (0.42) | GHSRPPARAHCRTR2CYP3A4UGCG | |
| SCHEMBL6162501 | 0.87 | PPARA (0.42) | GHSRPPARAHCRTR2CYP3A4UGCG | |
| SCHEMBL8413200 | 0.85 | PPARA (0.43) | GHSRPPARAHCRTR2CCKBRCTSS | |
| SCHEMBL6162692 | 0.84 | NR1H2 (0.48) | KMT2AGHSRPPARAHCRTR2CYP3A4 | |
| SCHEMBL6162688 | 0.84 | NR1H2 (0.48) | KMT2AGHSRPPARAHCRTR2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0721455-B9 | TETRAHYDROPYRIDINE-(OR 4-HYDROXYPIPERIDINE)ALKYLAZOLES HAVING AN AFFINITY FOR SIGMA AND/OR 5HT1A RECEPTORS | ESTEVE LABOR DR (ES) | 2005-04-20 | — | — | EP | claimed |
| EP-0721455-B1 | TETRAHYDROPYRIDINE-(OR 4-HYDROXYPIPERIDINE)ALKYLAZOLES HAVING AN AFFINITY FOR SIGMA AND/OR 5HT1A RECEPTORS | ESTEVE LABOR DR (ES) | 2002-12-11 | — | — | EP | claimed |
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | disclosed |