Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM6 | O15303 | 7/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | HPGD | P15428 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | GRM5 | P41594 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 4/20 | 0.50 |
| ▸ | CISD2 | Q8N5K1 | 2/20 | 0.50 |
| ▸ | PRKCI | P41743 | 1/20 | 0.46 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6159255 | 0.86 | GRM6 (0.78) | GRM6ALDH1A1HPGDGRM5MAPT | |
| SCHEMBL6160814 | 0.83 | GRM6 (1.00) | GRM6ALDH1A1HPGDGRM5HSD17B10 | |
| SCHEMBL7207512 | 0.82 | GRM6 (0.71) | GRM6ALDH1A1HPGDGRM5HSD17B10 | |
| SCHEMBL6157860 | 0.74 | TP53 (0.75) | GRM6ALDH1A1HPGDLMNAGRM5 | |
| SCHEMBL12297930 | 0.73 | ALDH1A1 (0.67) | GRM6ALDH1A1HPGDLMNAGRM5 | |
| SCHEMBL10714368 | 0.73 | GRM6 (1.00) | GRM6ALDH1A1HPGDLMNAGRM5 | |
| SCHEMBL10489630 | 0.71 | GRM6 (0.71) | GRM6ALDH1A1HPGDGRM5HSD17B10 | |
| SCHEMBL14414355 | 0.70 | GRM6 (0.77) | GRM6ALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL14485713 | 0.70 | OPRD1 (0.56) | GRM6ALDH1A1HPGDLMNAGRM5 | |
| SCHEMBL4217459 | 0.69 | GRM6 (1.00) | GRM6ALDH1A1HPGDGRM5HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6849738-B2 | Processes for the production of thienopyrimidine derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2005-02-01 | — | — | US | disclosed |
| US-20030055269-A1 | Processes for the production of thienopyrimidine derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2003-03-20 | — | — | US | disclosed |
| EP-1266898-A1 | PROCESSES FOR THE PRODUCTION OF THIENOPYRIMIDINE DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 2002-12-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030055269-A1 | Processes for the production of thienopyrimidine derivatives | GNRHR, NR5A1, DHODH | GRM6 136/4885ALDH1A1 1334/4885HPGD 430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.