SCHEMBL6161192

SCHEMBL6161192

CCC(C)(C)OOC(CC)(CC)C(=O)O

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.35
ALDH1A1 P00352 2/20 0.35
TDP1 Q9NUW8 1/20 0.35
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31
HIF1A Q16665 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8509557 0.85 LMNA (0.33) ALDH1A1
SCHEMBL140876 0.85 S1PR4 (0.30)
SCHEMBL138135 0.84 TSHR (0.38) TSHRALDH1A1TDP1CYP2D6CYP2C19
Acetic Acid SCHEMBL29229984 0.80 TSHR (0.41) TSHRALDH1A1TDP1CYP2D6CYP2C19
SCHEMBL15375591 0.79 TSHR (0.36) TSHRALDH1A1TDP1CYP2D6CYP2C19
SCHEMBL3266316 0.77 TSHR (0.35) TSHRALDH1A1TDP1CYP2D6CYP2C19
SCHEMBL22773843 0.77 ADORA3 (0.35) TSHRALDH1A1TDP1CYP2D6CYP2C19
SCHEMBL28610307 0.77 CTSK (0.33)
SCHEMBL208906 0.75 CES2 (0.30) ALDH1A1
Methyl Alcohol SCHEMBL8027284 0.74 TSHR (0.50) TSHRALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050239968-A1 Process for preparing graft polyols using enol ethers as reaction moderators BASF CORPORATION 2005-10-27 US disclosed
EP-1589051-A1 Process for preparing graft polyols using enol ethers as reaction moderators BASF Corporation (US) 2005-10-26 EP disclosed
EP-1192198-A1 PROCESS FOR MAKING GRAFT POLYOLS USING T-AMYL PEROXY FREE RADICAL INITIATOR BASF CORPORATION (US) 2002-04-03 EP disclosed
US-6172164-B1 POLYMERIZING AN ETHYLENICALLY UNSATURATED MONOMER WITH A MACROMER WITH UNSATURATION IN PRESENCE OF FREE RADICAL INITIATOR BLEND OF TERT-AMYL PEROXY (2-ETHYLHEXANOATE AND 1,1'BIS(TERT-AMYL PEROXY) CYCLOHEXANE BASF CORPORATION 2001-01-09 US disclosed
WO-2000068192-A2 PROCESS FOR THE PREPARATION OF (DI)ALKYLPEROXY ESTERS OF (DI)CARBOXYLIC ACIDS AKZO NOBEL N.V. (NL) 2000-11-16 WO disclosed
WO-2000059971-A1 PROCESS FOR MAKING GRAFT POLYOLS USING T-AMYL PEROXY FREE RADICAL INITIATOR BASF CORPORATION (DE) 2000-10-12 WO disclosed