Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.47 |
| ▸ | FAP | Q12884 | 2/20 | 0.47 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.47 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TPH1 | P17752 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | AKT2 | P31751 | 1/20 | 0.39 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5569674 | 0.86 | DPP4 (0.48) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL14938754 | 0.86 | DPP4 (0.48) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL16060347 | 0.86 | DPP4 (0.48) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL5109806 | 0.85 | DPP4 (0.47) | DPP4FAPDPP8DPP9DPP7 | |
| Hydrochloric Acid SCHEMBL5569670 | 0.85 | ALDH1A1 (0.49) | DPP4FAPDPP8DPP9DPP7 | |
| Hydrochloric Acid SCHEMBL16060346 | 0.85 | ALDH1A1 (0.49) | DPP4FAPDPP8DPP9DPP7 | |
| Hydrochloric Acid SCHEMBL5569672 | 0.85 | ALDH1A1 (0.49) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL6161194 | 0.85 | DPP4 (0.47) | DPP4FAPDPP8DPP9DPP7 | |
| Hydrochloric Acid SCHEMBL5148984 | 0.84 | DPP4 (0.46) | DPP4FAPDPP8DPP9DPP7 | |
| Hydrochloric Acid SCHEMBL5112988 | 0.84 | DPP4 (0.46) | DPP4FAPDPP8DPP9DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7084250-B2 | Process for the preparation of acetyl-amidiniophenylalanyl-cyclohexylglycyl-pyridinioalaninamides | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2006-08-01 | — | — | US | disclosed |
| EP-1254159-B9 | PROCESS FOR THE PREPARATION OF ACETYL-AMIDINIOPHENYLALANYL-CYCLOHEXYLGLYCYL-PYRIDYLALANINAMIDES | SANOFI AVENTIS DEUTSCHLAND (DE) | 2006-06-28 | — | — | EP | disclosed |
| EP-1254159-B1 | PROCESS FOR THE PREPARATION OF ACETYL-AMIDINIOPHENYLALANYL-CYCLOHEXYLGLYCYL-PYRIDYLALANINAMIDES | SANOFI AVENTIS DEUTSCHLAND (DE) | 2006-05-10 | — | — | EP | disclosed |
| US-20040225109-A1 | Process for the preparation of acetyl-amidiniophenylalanyl-cyclohexylglycyl-pyridinioalaninamides | AVENTIS PHARMA DEUTSCHLAND GMBH | 2004-11-11 | — | — | US | disclosed |
| EP-1254159-A2 | PROCESS FOR THE PREPARATION OF ACETYL-AMIDINIOPHENYLALANYL-CYCLOHEXYLGLYCYL-PYRIDINIOALANINAMIDES | Aventis Pharma Deutschland GmbH (DE) | 2002-11-06 | — | — | EP | disclosed |
| EP-0868526-B1 | PROCESS FOR PREPARING N-ACETYL(L)-4-CYANOPHENYLALANINE Ac-(L)-Phe(4-CN)-OH AND N-ACETYL-(L)-p-AMIDINOPHENYLALANINE-CYCLOHEXYLGLYCINE-BETA-(3-N-METHYLPYRIDINIUM)-ALANINE Ac-(L)-pAph-Chg-PalMe(3)-NH2 | AVENTIS PHARMA INC (US) | 2002-08-14 | — | — | EP | disclosed |
| US-20010031858-A1 | Process for the preparation of acetyl-amidiniophenylalanyl-cyclohexylglycyl-pyridinioalaninamides | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2001-10-18 | — | — | US | disclosed |
| WO-2001055175-A2 | PROCESS FOR THE PREPARATION OF ACETYL-AMIDINIOPHENYLALANYL-CYCLOHEXYLGLYCYL-PYRIDINIOALANINAMIDES | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-08-02 | — | — | WO | disclosed |
| EP-0868526-A1 | NOVEL PROCESS FOR PREPARING N-ACETYL(L)-4-CYANOPHENYLALANINE Ac-(L)-Phe(4-CN)-OH AND N-ACETYL-(L)-p-AMIDINOPHENYLALANINE-CYCLOHEXYLGLYCINE-$g(b)-(3-N-METHYLPYRIDINIUM)-ALANINE Ac-(L)-pAph-Chg-PalMe(3)-NH 2? | HOECHST MARION ROUSSEL, INC. (US) | 1998-10-07 | — | — | EP | disclosed |
| WO-1997022712-A1 | NOVEL PROCESS FOR PREPARING N-ACETYL(L)-4-CYANOPHENYLALANINE Ac-(L)-Phe(4-CN)-OH AND N-ACETYL-(L)-p-AMIDINOPHENYLALANINE-CYCLOHEXYLGLYCINE-β-(3-N-METHYLPYRIDINIUM)-ALANINE Ac-(L)-pAph-Chg-PalMe(3)-NH¿2? | HOECHST MARION ROUSSEL, INC. (US) | 1997-06-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040225109-A1 | Process for the preparation of acetyl-amidiniophenylalanyl-cyclohexylglycyl-pyridinioalaninamides | SERPINC1, F12, F11 | DPP4 525/4885FAP 649/4885DPP8 697/4885 |
| US-20010031858-A1 | Process for the preparation of acetyl-amidiniophenylalanyl-cyclohexylglycyl-pyridinioalaninamides | SERPINC1, F12, F11 | DPP4 525/4885FAP 649/4885DPP8 697/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.