SCHEMBL6161360

SCHEMBL6161360

CC(C)(C)OC(=O)NC(C)(C)C(=O)N[C@H](COCc1ccccc1)C(=O)N1CCC(C(N)=O)(N2CCCCC2)CC1

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GHSR Q92847 2/20 0.48
PPARA Q07869 2/20 0.44
TSHR P16473 1/20 0.43
CTSS P25774 1/20 0.42
ALDH1A1 P00352 2/20 0.41
TP53 P04637 1/20 0.41
PPARG P37231 1/20 0.41
UGCG Q16739 2/20 0.40
CTSL P07711 1/20 0.40
CYP3A4 P08684 1/20 0.40
KDM4E B2RXH2 1/20 0.40
MAPT P10636 1/20 0.40
KLK7 P49862 1/20 0.39
KLK5 Q9Y337 1/20 0.39
TACR1 P25103 1/20 0.39
ITGB3 P05106 1/20 0.38
ITGA2B P08514 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6164148 0.87 GHSR (0.59) GHSRTSHRALDH1A1TP53UGCG
SCHEMBL6162874 0.83 GHSR (0.48) GHSRPPARACTSSPPARGUGCG
SCHEMBL6164692 0.82 GHSR (0.48) GHSRPPARATSHRCTSSPPARG
SCHEMBL6164689 0.82 GHSR (0.48) GHSRPPARATSHRCTSSPPARG
SCHEMBL6163100 0.82 GHSR (0.61) GHSRUGCGCYP3A4TACR1
SCHEMBL6162877 0.80 GHSR (0.46) GHSRPPARACTSSPPARGUGCG
SCHEMBL6162074 0.80 GHSR (0.46) GHSRPPARACTSSPPARGUGCG
SCHEMBL6163155 0.80 GHSR (0.46) GHSRPPARATSHRCTSSPPARG
SCHEMBL6162072 0.80 GHSR (0.46) GHSRPPARACTSSPPARGUGCG
SCHEMBL6162935 0.80 PPARA (0.48) GHSRPPARACTSSPPARGKLK7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0828754-B1 DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE PFIZER (US) 2005-02-02 EP disclosed