Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRR | Q9GZT4 | 2/20 | 0.48 |
| ▸ | PSAT1 | Q9Y617 | 2/20 | 0.48 |
| ▸ | ALPI | P09923 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | XIAP | P98170 | 1/20 | 0.45 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 6/20 | 0.43 |
| ▸ | PPARA | Q07869 | 5/20 | 0.43 |
| ▸ | GRB2 | P62993 | 1/20 | 0.43 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.43 |
| ▸ | MC4R | P32245 | 1/20 | 0.42 |
| ▸ | MC5R | P33032 | 1/20 | 0.42 |
| ▸ | MC3R | P41968 | 1/20 | 0.42 |
| ▸ | TPH1 | P17752 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3052070 | 0.91 | ALPI (0.54) | SRRALPIPKMPTGS1XIAP | |
| SCHEMBL1676744 | 0.86 | MKNK1 (0.45) | DPP4 | |
| SCHEMBL11401894 | 0.84 | DPP4 (0.44) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Trifluoroacetic Acid SCHEMBL6161399 | 0.81 | SLC7A5 (0.66) | SRRPSAT1ALPIPKMPTGS1 | |
| Hydrochloric Acid SCHEMBL31407378 | 0.81 | SRR (0.50) | SRRPSAT1ALPIPKMPTGS1 | |
| SCHEMBL2720884 | 0.80 | SRR (0.50) | SRRPSAT1ALPIPKMPTGS1 | |
| SCHEMBL16415824 | 0.78 | CTSK (0.47) | SRRPSAT1ALPIPKMPTGS1 | |
| SCHEMBL7451018 | 0.78 | SRR (0.54) | SRRPSAT1ALPIPKMPTGS1 | |
| SCHEMBL539324 | 0.78 | SRR (0.54) | SRRPSAT1ALPIPKMPTGS1 | |
| SCHEMBL539325 | 0.78 | SRR (0.54) | SRRPSAT1ALPIPKMPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | disclosed |
| US-5936089-A | PIPERIDINE DERIVATIVES; BONE DISORDERS; OBESITY; AGING; CACHEXIA ASSOCIATED WITH AIDS AND CANCER | PFIZER INC (US) | 1999-08-10 | — | — | US | disclosed |
| WO-1996035713-A1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER, INC. (US) | 1996-11-14 | — | — | WO | disclosed |