Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 5/20 | 0.45 |
| ▸ | MKNK2 | Q9HBH9 | 5/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | LTK | P29376 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6161407 | 0.86 | SRR (0.48) | DPP4 | |
| Hydrochloric Acid SCHEMBL31407496 | 0.84 | MKNK1 (0.45) | MKNK1MKNK2CYP2A6NAAANR3C2 | |
| Trifluoroacetic Acid SCHEMBL1676739 | 0.83 | GRB2 (0.53) | MKNK1MKNK2CYP2A6NR3C2DPP4 | |
| SCHEMBL539487 | 0.82 | MKNK1 (0.50) | MKNK1MKNK2CYP2A6NAAAKDR | |
| SCHEMBL1676927 | 0.81 | MKNK1 (0.47) | MKNK1MKNK2CYP2A6NAAAMMP12 | |
| SCHEMBL1676925 | 0.81 | MKNK1 (0.47) | MKNK1MKNK2CYP2A6NAAAMMP12 | |
| Hydrochloric Acid SCHEMBL539488 | 0.81 | MKNK1 (0.49) | MKNK1MKNK2CYP2A6NAAAWNT3A | |
| Hydrochloric Acid SCHEMBL539486 | 0.81 | MKNK1 (0.49) | MKNK1MKNK2CYP2A6NAAAWNT3A | |
| SCHEMBL7606896 | 0.79 | SLC7A5 (0.56) | MKNK1MKNK2CYP2A6 | |
| SCHEMBL21690091 | 0.79 | SLC7A5 (0.56) | MKNK1MKNK2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110098477-A1 | Method Of Producing Compound Having Anti-Hcv Activity | CHUGAI SEIYAKU KABUSHIKI KAISHA | 2011-04-28 | — | — | US | disclosed |
| EP-1908846-A1 | METHOD OF PRODUCING COMPOUND HAVING ANTI-HCV ACTION | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2008-04-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110098477-A1 | Method Of Producing Compound Having Anti-Hcv Activity | ERG28, HCCS, BCAT2 | MKNK1 2163/4885MKNK2 2897/4885CYP2A6 489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.