Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | GSR | P00390 | 1/20 | 0.47 |
| ▸ | CHAT | P28329 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.43 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5254661 | 0.83 | ALDH1A1 (0.48) | ALDH1A1GSRCHATHDAC1HDAC8 | |
| SCHEMBL5254658 | 0.83 | ALDH1A1 (0.48) | ALDH1A1GSRCHATHDAC1HDAC8 | |
| SCHEMBL31500768 | 0.80 | ALDH1A1 (0.48) | ALDH1A1GSRCHATHDAC1HDAC8 | |
| SCHEMBL5455154 | 0.80 | ALDH1A1 (0.48) | ALDH1A1GSRCHATHDAC1HDAC8 | |
| SCHEMBL7283509 | 0.80 | ALDH1A1 (0.48) | ALDH1A1GSRCHATHDAC1HDAC8 | |
| SCHEMBL6568108 | 0.78 | CHAT (0.47) | ALDH1A1GSRCHATHDAC1HDAC8 | |
| SCHEMBL10590630 | 0.78 | ALDH1A1 (0.46) | ALDH1A1GSRCHATHDAC1HDAC8 | |
| SCHEMBL29528779 | 0.78 | CHAT (0.47) | ALDH1A1GSRCHATHDAC1HDAC8 | |
| SCHEMBL3533801 | 0.78 | HDAC1 (0.47) | ALDH1A1GSRCHATHDAC1HDAC8 | |
| SCHEMBL2095735 | 0.78 | HDAC1 (0.47) | ALDH1A1GSRCHATHDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1505156-B1 | Process for the enantioselective preparation of secondary alcohols by lipase catalysed solvolysis of the corresponding acetoacetic acid ester | CONSORTIUM ELEKTROCHEM IND (DE) | 2005-12-07 | — | — | EP | disclosed |
| US-20050032182-A1 | Process for the enantioselective preparation of secondary alcohols by lipase-catalyzed solvolysis of the corresponding acetoacetic esters | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH | 2005-02-10 | — | — | US | disclosed |
| EP-1505156-A1 | Process for the enantioselective preparation of secondary alcohols by lipase catalysed solvolysis of the corresponding acetoacetic acid ester | Consortium für elektrochemische Industrie GmbH (DE) | 2005-02-09 | — | — | EP | disclosed |
| CN-1010947-B | PROCESS FOR PREPN. OF PYRIDOPYRIMIDINES COMPOUNDS | BAYER AG (DE) | 1990-12-26 | — | — | CN | disclosed |
| CN-86100279-A | The method for preparing the Pyridopyrimidine compounds | — | 1986-11-19 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050032182-A1 | Process for the enantioselective preparation of secondary alcohols by lipase-catalyzed solvolysis of the corresponding acetoacetic esters | LIPC, LIPE, LIPA | ALDH1A1 187/4885GSR 2951/4885CHAT 1402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.