Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CHAT | P28329 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | GSR | P00390 | 1/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.44 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7283509 | 1.00 | ALDH1A1 (0.48) | ALDH1A1CHATHDAC1HDAC8HDAC6 | |
| SCHEMBL31500768 | 1.00 | ALDH1A1 (0.48) | ALDH1A1CHATHDAC1HDAC8HDAC6 | |
| SCHEMBL30444012 | 0.80 | HDAC1 (0.47) | ALDH1A1CHATHDAC1HDAC8HDAC6 | |
| SCHEMBL12426097 | 0.80 | ALDH1A1 (0.46) | ALDH1A1CHATHDAC1HDAC8HDAC6 | |
| SCHEMBL29528779 | 0.80 | CHAT (0.47) | ALDH1A1CHATHDAC1HDAC8HDAC6 | |
| SCHEMBL6568108 | 0.80 | CHAT (0.47) | ALDH1A1CHATHDAC1HDAC8HDAC6 | |
| SCHEMBL10590630 | 0.80 | ALDH1A1 (0.46) | ALDH1A1CHATHDAC1HDAC8HDAC6 | |
| SCHEMBL3533797 | 0.80 | HDAC1 (0.47) | ALDH1A1CHATHDAC1HDAC8HDAC6 | |
| SCHEMBL3533801 | 0.80 | HDAC1 (0.47) | ALDH1A1CHATHDAC1HDAC8HDAC6 | |
| SCHEMBL6161586 | 0.80 | ALDH1A1 (0.52) | ALDH1A1CHATHDAC1HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100029622-A1 | MICROEMULSIONS | NEUROSCIENZE PHARMANESS S.C.A.R.L. (IT) | 2010-02-04 | — | — | US | disclosed |
| US-20100029622-A1 | MICROEMULSIONS | NEUROSCIENZE PHARMANESS S.C.A.R.L. (IT) | 2010-02-04 | — | — | US | disclosed |
| EP-2149370-A1 | Diazabicyclic compounds and microemulsions thereof | Neuroscienze Pharmaness S.C. A R.L. (IT) | 2010-02-03 | — | — | EP | disclosed |
| US-20070225269-A1 | Use of (3-(1-(3-Phenyl-Propenyl)-Piperidin-4-Yl)-2,3-Dihydro-Indol-1-Yl)-(Pyridin-4-Yl)-Methanonone Derivatives and Related Compounds as Insecticides | SYNGENTA CROP PROTECTION, INC. | 2007-09-27 | — | — | US | disclosed |
| CN-1250546-C | Tetrahydropyrido compound | ALTANA PHARMA (DE) | 2006-04-12 | — | — | CN | disclosed |
| CN-1508136-A | Tetrahydropyrido compound | ��̹��ҽҩ��˾ | 2004-06-30 | — | — | CN | disclosed |
| CN-1251102-A | Tetrahydropyrido compounds | BYK GULDEN LOMBERG CHEM FAB (DE) | 2000-04-19 | — | — | CN | disclosed |
| US-5068325-A | Dopaminergic systems as hypotensives, sedatives, antitussives and/or antiphlogistics | KARL THOMAE GMBH (DE) | 1991-11-26 | — | — | US | disclosed |
| US-4746712-A | GELATION INHIBITION | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1988-05-24 | — | — | US | disclosed |
| US-4695614-A | ORGANOALUMINUM COMPOUND, MODIFIED VANADIUM COMPOUND | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1987-09-22 | — | — | US | disclosed |
| US-4616086-A | ANTICOAGULANTS | BOEHRINGER MANNHEIM GMBH (DE) | 1986-10-07 | — | — | US | disclosed |
| US-4115398-A | CARDIOVASCULAR DISORDERS | KOWA COMPANY LTD. (JP) | 1978-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029622-A1 | MICROEMULSIONS | LIPA, APOB, LIPC | ALDH1A1 4424/4885CHAT 620/4885HDAC1 3197/4885 |
| US-20070225269-A1 | Use of (3-(1-(3-Phenyl-Propenyl)-Piperidin-4-Yl)-2,3-Dihydro-Indol-1-Yl)-(Pyridin-4-Yl)-Methanonone Derivatives and Related Compounds as Insecticides | CHRM1, NPY1R, MRM1 | ALDH1A1 465/4885CHAT 811/4885HDAC1 2886/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.