Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GABRP | O00591 | 1/20 | 0.43 |
| ▸ | GABRD | O14764 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.43 |
| ▸ | GABRE | P78334 | 1/20 | 0.43 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5034667 | 0.83 | P2RX7 (0.51) | P2RX7KDM4EALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL3512015 | 0.81 | P2RX7 (0.53) | P2RX7KDM4EALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL12500156 | 0.78 | NPC1 (0.57) | KDM4EALDH1A1SMN1; SMN2GAAMAPT | |
| SCHEMBL161323 | 0.78 | NNMT (0.61) | P2RX7KDM4EALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL24931102 | 0.78 | KDM4E (0.74) | P2RX7KDM4EALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL13952836 | 0.78 | GABRP (0.42) | ALDH1A1SMN1; SMN2KMT2AGABRPGABRD | |
| SCHEMBL30242327 | 0.76 | SMN1; SMN2 (0.67) | P2RX7KDM4EALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL24571681 | 0.76 | MEN1 (0.54) | KDM4EALDH1A1SMN1; SMN2KMT2AMAPT | |
| SCHEMBL10650237 | 0.76 | NPC1 (0.45) | P2RX7KDM4ESMN1; SMN2GAAKMT2A | |
| SCHEMBL25866684 | 0.76 | SMN1; SMN2 (0.67) | P2RX7KDM4EALDH1A1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3325446-A1 | SUBSTITUTED ARYL AND HETEROARYL CARBOXYLIC ACID HYDRAZIDES OR SALTS THEREOF AND USE THEREOF TO INCREASE STRESS TOLERANCE IN PLANTS | Bayer CropScience Aktiengesellschaft (DE) | 2018-05-30 | — | — | EP | disclosed |
| WO-2017012966-A1 | SUBSTITUTED ARYL AND HETEROARYL CARBOXYLIC ACID HYDRAZIDES OR SALTS THEREOF AND USE THEREOF TO INCREASE STRESS TOLERANCE IN PLANTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-01-26 | — | — | WO | disclosed |
| EP-1492784-A2 | SUBSTITUTED 2,3-DIPHENYL PYRIDINES | Merck & Co., Inc. (US) | 2005-01-05 | — | — | EP | disclosed |
| WO-2003082191-A2 | SUBSTITUTED 2,3-DIPHENYL PYRIDINES | MERCK & CO., INC. (US) | 2003-10-09 | — | — | WO | disclosed |