Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.67 |
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | CASP3 | P42574 | 2/20 | 0.55 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.55 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.55 |
| ▸ | RELA | Q04206 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 6/20 | 0.44 |
| ▸ | CA9 | Q16790 | 6/20 | 0.44 |
| ▸ | CA4 | P22748 | 4/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30242327 | 1.00 | SMN1; SMN2 (0.67) | SMN1; SMN2RAB9ANPC1CASP3SENP8 | |
| SCHEMBL25866687 | 0.80 | SMN1; SMN2 (0.65) | SMN1; SMN2RAB9ANPC1CASP3SENP8 | |
| SCHEMBL28779577 | 0.80 | P2RX7 (0.54) | SMN1; SMN2RAB9ANPC1CASP3SENP8 | |
| SCHEMBL29647658 | 0.80 | P2RX7 (0.54) | SMN1; SMN2RAB9ANPC1CASP3SENP8 | |
| SCHEMBL6161620 | 0.76 | P2RX7 (0.56) | SMN1; SMN2MAPTALDH1A1P2RX7KDM4E | |
| SCHEMBL31220152 | 0.74 | P2RX7 (0.45) | SMN1; SMN2RAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL3512015 | 0.73 | P2RX7 (0.53) | SMN1; SMN2RAB9ANPC1L3MBTL1MAPT | |
| SCHEMBL3491462 | 0.72 | CTSD (0.53) | L3MBTL1MAPTALDH1A1P2RX7CA2 | |
| SCHEMBL30353943 | 0.72 | SMN1; SMN2 (0.61) | SMN1; SMN2RAB9ANPC1CASP3SENP8 | |
| SCHEMBL25866749 | 0.72 | SMN1; SMN2 (0.61) | SMN1; SMN2RAB9ANPC1CASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230234926-A1 | 2-(3-(2-METHYL-6-(P-TOLYL) PYRIDINE-3-YL) UREIDO) BENZENESULFONAMIDE AND DERIVATIVES AS INHIBITOR OF CARBONIC ANHYDRASE IX FOR THE TREATMENT OF CANCER | YEDITEPE UNIVERSITESI (TR) | 2023-07-27 | — | — | US | disclosed |
| US-20230234926-A1 | 2-(3-(2-METHYL-6-(P-TOLYL) PYRIDINE-3-YL) UREIDO) BENZENESULFONAMIDE AND DERIVATIVES AS INHIBITOR OF CARBONIC ANHYDRASE IX FOR THE TREATMENT OF CANCER | YEDITEPE UNIVERSITESI (TR) | 2023-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230234926-A1 | 2-(3-(2-METHYL-6-(P-TOLYL) PYRIDINE-3-YL) UREIDO) BENZENESULFONAMIDE AND DERIVATIVES AS INHIBITOR OF CARBONIC ANHYDRASE IX FOR THE TREATMENT OF CANCER | CA9, CA6, CA2 | SMN1; SMN2 4462/4885RAB9A 1370/4885NPC1 4491/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.