Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 6/20 | 0.53 |
| ▸ | HTR2C | P28335 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HTR1D | P28221 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | HTR7 | P34969 | 2/20 | 0.49 |
| ▸ | QDPR | P09417 | 3/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.46 |
| ▸ | MARK3 | P27448 | 1/20 | 0.46 |
| ▸ | PRKCI | P41743 | 1/20 | 0.46 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16874873 | 0.89 | HTR6 (0.61) | HTR6HTR2CKDM4EMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL16874840 | 0.89 | HTR6 (0.61) | HTR6HTR2CKDM4EMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6739875 | 0.84 | HTR2C (0.61) | HTR6HTR2CKDM4EMEN1ALDH1A1 | |
| SCHEMBL6162919 | 0.83 | HTR2C (0.47) | HTR6HTR2CHTR7QDPRJAK2 | |
| SCHEMBL894220 | 0.82 | QDPR (0.60) | HTR6HTR2CKDM4EMEN1ALDH1A1 | |
| SCHEMBL6586935 | 0.80 | QDPR (0.50) | HTR6HTR2CKDM4EMEN1ALDH1A1 | |
| SCHEMBL5542320 | 0.76 | HTR2C (0.49) | HTR6HTR2CKDM4EMEN1ALDH1A1 | |
| SCHEMBL27025891 | 0.76 | HTR2C (0.44) | HTR6HTR2CHTR7QDPRTGFBR1 | |
| Hydrochloric Acid SCHEMBL16874680 | 0.75 | QDPR (0.52) | HTR6HTR2CKDM4EMEN1ALDH1A1 | |
| SCHEMBL27007677 | 0.75 | HTR2C (0.47) | HTR2CKDM4EALDH1A1MAPTQDPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755923-B1 | Ameliorant or remedy for symptoms caused by Ischemic diseases and Phenylpiperidine compounds useful therefor | DAIICHI SUNTORY PHARMA CO LTD (JP) | 2005-05-04 | — | — | EP | disclosed |
| US-6469010-B1 | COMPOSITION ALSO FOR ALLEVIATION OR TREATMENT OF SYMPTOMS DERIVED FROM SEIZURES, EPILEPSY AND MIGRAINE HEADACHES, AND SUPPRESSION OF CALCIUM ION OVERLOAD | SUNTORY LIMITED (JP) | 2002-10-22 | — | — | US | disclosed |
| EP-0755923-A1 | AMELIORANT OR REMEDY FOR SYMPTOMS CAUSED BY ISCHEMIC DISEASES AND COMPOUNDS USEFUL THEREFOR | SUNTORY LIMITED (JP) | 1997-01-29 | — | — | EP | disclosed |