Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QDPR | P09417 | 3/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP3 | P08254 | 1/20 | 0.50 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 7/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | HTR6 | P50406 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTR1D | P28221 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7394377 | 0.88 | HTR2C (0.60) | QDPRCD274HTR2CSIGMAR1HTR6 | |
| SCHEMBL6587898 | 0.88 | QDPR (0.60) | QDPRCD274HTR2CSIGMAR1HTR6 | |
| Hydrochloric Acid SCHEMBL4789235 | 0.87 | HTR2C (0.61) | QDPRHTR2CSIGMAR1HTR6KDM4E | |
| SCHEMBL6584948 | 0.83 | SIGMAR1 (0.65) | QDPRHTR2CSIGMAR1HTR6HTR7 | |
| SCHEMBL14704745 | 0.80 | QDPR (0.51) | QDPRCD274HTR2CSIGMAR1HTR6 | |
| SCHEMBL6161994 | 0.80 | HTR6 (0.53) | QDPRHTR2CSIGMAR1HTR6KDM4E | |
| SCHEMBL6585457 | 0.80 | HTR2C (0.76) | QDPRHTR2CSIGMAR1 | |
| SCHEMBL16874873 | 0.79 | HTR6 (0.61) | QDPRHTR2CHTR6KDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL16874840 | 0.79 | HTR6 (0.61) | QDPRHTR2CHTR6KDM4EMEN1 | |
| SCHEMBL6590672 | 0.78 | QDPR (0.54) | QDPRMMP2MMP3CD274HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036062-B1 | HYDROXAMIC ACID DERIVATIVES AS MATRIX METALLOPROTEASE (MMP) INHIBITORS | PFIZER LTD (GB) | 2004-01-02 | — | — | EP | disclosed |
| US-6495568-B1 | TREATMENT OF TISSUE ULCERATION, WOUND REPAIR AND SKIN DISEASES | WARNER-LAMBERT COMPANY | 2002-12-17 | — | — | US | disclosed |