Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KHK | P50053 | 1/20 | 0.54 |
| ▸ | QDPR | P09417 | 3/20 | 0.52 |
| ▸ | HTR2C | P28335 | 5/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.50 |
| ▸ | HTR6 | P50406 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HTR1D | P28221 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | PTGIR | P43119 | 1/20 | 0.44 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL894220 | 0.91 | QDPR (0.60) | KHKQDPRHTR2CSIGMAR1HTR6 | |
| Hydrochloric Acid SCHEMBL6739875 | 0.89 | HTR2C (0.61) | KHKQDPRHTR2CSIGMAR1HTR6 | |
| SCHEMBL14704894 | 0.81 | QDPR (0.54) | KHKQDPRHTR2CSIGMAR1HTR6 | |
| Hydrochloric Acid SCHEMBL16874680 | 0.80 | QDPR (0.52) | KHKQDPRHTR2CSIGMAR1HTR6 | |
| SCHEMBL3032622 | 0.80 | HTR2C (0.54) | KHKQDPRHTR2CSIGMAR1HTR6 | |
| Water SCHEMBL7966495 | 0.78 | QDPR (0.58) | KHKQDPRHTR2CSIGMAR1HTR6 | |
| 1,2,3,4-Tetrahydroisoquinoline SCHEMBL28142548 | 0.77 | PNMT (0.51) | KHKQDPRHTR2CSIGMAR1HTR6 | |
| SCHEMBL9974662 | 0.77 | HTR2C (0.59) | QDPRHTR2CSIGMAR1HTR6 | |
| SCHEMBL14085315 | 0.75 | QDPR (0.43) | KHKQDPRHTR2CSIGMAR1HTR6 | |
| SCHEMBL6161994 | 0.74 | HTR6 (0.53) | KHKQDPRHTR2CSIGMAR1HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755923-B1 | Ameliorant or remedy for symptoms caused by Ischemic diseases and Phenylpiperidine compounds useful therefor | DAIICHI SUNTORY PHARMA CO LTD (JP) | 2005-05-04 | — | — | EP | disclosed |
| US-6469010-B1 | COMPOSITION ALSO FOR ALLEVIATION OR TREATMENT OF SYMPTOMS DERIVED FROM SEIZURES, EPILEPSY AND MIGRAINE HEADACHES, AND SUPPRESSION OF CALCIUM ION OVERLOAD | SUNTORY LIMITED (JP) | 2002-10-22 | — | — | US | disclosed |
| US-6048876-A | ANTICONVULSANTS; ANTIEPILEPIC AGENT | SUNTORY LIMITED (JP) | 2000-04-11 | — | — | US | disclosed |
| EP-0755923-A1 | AMELIORANT OR REMEDY FOR SYMPTOMS CAUSED BY ISCHEMIC DISEASES AND COMPOUNDS USEFUL THEREFOR | SUNTORY LIMITED (JP) | 1997-01-29 | — | — | EP | disclosed |