Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.41 |
| ▸ | OGFRL1 | Q5TC84 | 5/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CCKBR | P32239 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 3/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6162290 | 1.00 | FPR2 (0.41) | FPR2OPRM1OGFRL1OPRD1OPRK1 | |
| SCHEMBL6165477 | 0.91 | KMT2A (0.49) | FPR2OPRM1OGFRL1OPRD1OPRK1 | |
| SCHEMBL6165473 | 0.91 | KMT2A (0.49) | FPR2OPRM1OGFRL1OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL6163290 | 0.86 | BRD4 (0.44) | FPR2OPRM1OGFRL1OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL6163287 | 0.86 | BRD4 (0.44) | FPR2OPRM1OGFRL1OPRD1OPRK1 | |
| SCHEMBL6165912 | 0.83 | MEN1 (0.51) | FPR2KMT2ACCKBR | |
| SCHEMBL6165907 | 0.83 | MEN1 (0.51) | FPR2KMT2ACCKBR | |
| SCHEMBL8409763 | 0.82 | OPRM1 (0.40) | FPR2OPRM1OGFRL1OPRD1OPRK1 | |
| SCHEMBL6179686 | 0.81 | F13A1 (0.49) | KMT2ACCKBRMAPK1ITGB3ITGA2B | |
| SCHEMBL6163831 | 0.78 | CALCRL (0.47) | FPR2OPRM1OGFRL1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | disclosed |