Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 8/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 7/20 | 0.40 |
| ▸ | OGFRL1 | Q5TC84 | 6/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CKS1B | P61024 | 1/20 | 0.34 |
| ▸ | SKP1 | P63208 | 1/20 | 0.34 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8409914 | 0.88 | OPRM1 (0.41) | OPRM1OPRD1OGFRL1OPRK1FPR2 | |
| SCHEMBL6162296 | 0.82 | FPR2 (0.41) | OPRM1OPRD1OGFRL1OPRK1FPR2 | |
| SCHEMBL6162290 | 0.82 | FPR2 (0.41) | OPRM1OPRD1OGFRL1OPRK1FPR2 | |
| SCHEMBL6165477 | 0.79 | KMT2A (0.49) | OPRM1OPRD1OGFRL1OPRK1FPR2 | |
| SCHEMBL6165473 | 0.79 | KMT2A (0.49) | OPRM1OPRD1OGFRL1OPRK1FPR2 | |
| SCHEMBL8412927 | 0.75 | OPRM1 (0.46) | OPRM1OPRK1OPRL1 | |
| SCHEMBL8410120 | 0.73 | SSTR3 (0.39) | OPRM1OPRD1OGFRL1FPR2 | |
| SCHEMBL6165912 | 0.71 | MEN1 (0.51) | FPR2 | |
| SCHEMBL6165907 | 0.71 | MEN1 (0.51) | FPR2 | |
| Hydrochloric Acid SCHEMBL6163287 | 0.69 | BRD4 (0.44) | OPRM1OPRD1OGFRL1OPRK1FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5936089-A | PIPERIDINE DERIVATIVES; BONE DISORDERS; OBESITY; AGING; CACHEXIA ASSOCIATED WITH AIDS AND CANCER | PFIZER INC (US) | 1999-08-10 | — | — | US | disclosed |