Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 4/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6162681 | 0.79 | OPRL1 (0.37) | OPRL1KCNH2OPRM1PABPC1MGLL | |
| SCHEMBL8219888 | 0.74 | KCNH2 (0.41) | KCNH2PABPC1 | |
| SCHEMBL6162587 | 0.72 | KDM4E (0.47) | OPRL1KCNH2OPRM1 | |
| SCHEMBL6159875 | 0.70 | HTR2A (0.54) | OPRL1KCNH2OPRM1DRD2 | |
| SCHEMBL6162676 | 0.68 | CHRNA7 (0.58) | DRD2 | |
| SCHEMBL3976528 | 0.68 | GABRA1 (0.50) | OPRL1OPRM1 | |
| SCHEMBL6160494 | 0.68 | SLC6A2 (0.53) | — | |
| SCHEMBL6158959 | 0.67 | MEN1 (0.51) | OPRL1KCNH2OPRM1DRD2 | |
| SCHEMBL6159481 | 0.67 | OPRL1 (0.44) | OPRL1KCNH2OPRM1 | |
| SCHEMBL6158951 | 0.67 | MEN1 (0.51) | OPRL1KCNH2OPRM1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755923-B1 | Ameliorant or remedy for symptoms caused by Ischemic diseases and Phenylpiperidine compounds useful therefor | DAIICHI SUNTORY PHARMA CO LTD (JP) | 2005-05-04 | — | — | EP | disclosed |
| US-6469010-B1 | COMPOSITION ALSO FOR ALLEVIATION OR TREATMENT OF SYMPTOMS DERIVED FROM SEIZURES, EPILEPSY AND MIGRAINE HEADACHES, AND SUPPRESSION OF CALCIUM ION OVERLOAD | SUNTORY LIMITED (JP) | 2002-10-22 | — | — | US | disclosed |
| EP-0755923-A1 | AMELIORANT OR REMEDY FOR SYMPTOMS CAUSED BY ISCHEMIC DISEASES AND COMPOUNDS USEFUL THEREFOR | SUNTORY LIMITED (JP) | 1997-01-29 | — | — | EP | disclosed |