SCHEMBL616263

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL615583	0.93	PTK2 (0.35)	ALOX5TUBB4ATUBBTUBA3CTUBA1B
	SCHEMBL617993	0.90	TUBB1 (0.41)	TUBB1MGAMGAASIMGAM2
	SCHEMBL618029	0.84	MGAM (0.49)	TUBB4ATUBBTUBA3CTUBA1BTUBA4A
	SCHEMBL619549	0.84	MGAM (0.44)	TUBB4ATUBBTUBA3CTUBA1BTUBA4A
	SCHEMBL618661	0.84	TUBB4A (0.44)	TUBB4ATUBBTUBA3CTUBA1BTUBA4A
	SCHEMBL617918	0.84	ALDH1A1 (0.39)	TUBB4ATUBBTUBA3CTUBA1BTUBA4A
	SCHEMBL618113	0.83	TUBB4A (0.46)	TUBB4ATUBBTUBA3CTUBA1BTUBA4A
	SCHEMBL618306	0.83	SLC10A2 (0.42)	TUBB4ATUBBTUBA3CTUBA1BTUBA4A
	SCHEMBL618668	0.83	CHEK1 (0.39)	TUBB4ATUBBTUBA3CTUBA1BTUBA4A
	SCHEMBL618380	0.83	EPHB4 (0.41)	ALOX5TUBB4ATUBBTUBA3CTUBA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.