Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL124625 | 0.87 | HTT (0.63) | SMN1; SMN2LMNAALDH1A1HTTPKM | |
| SCHEMBL6003633 | 0.85 | GPR35 (0.52) | CYP19A1SMN1; SMN2LMNAALDH1A1HTT | |
| SCHEMBL14940853 | 0.83 | CYP19A1 (0.50) | CYP19A1SMN1; SMN2LMNAALDH1A1HTT | |
| SCHEMBL6163411 | 0.82 | SMN1; SMN2 (0.53) | CYP19A1SMN1; SMN2LMNAALDH1A1HTT | |
| SCHEMBL2022935 | 0.81 | TSHR (0.67) | CYP19A1SMN1; SMN2LMNAALDH1A1HTT | |
| SCHEMBL28026309 | 0.81 | TSHR (0.67) | CYP19A1SMN1; SMN2LMNAALDH1A1HTT | |
| SCHEMBL11788134 | 0.79 | ALDH1A1 (0.56) | SMN1; SMN2LMNAALDH1A1HTTCRHBP | |
| SCHEMBL6156984 | 0.79 | CRHBP (0.65) | SMN1; SMN2ALDH1A1HTTCRHBPCRHR2 | |
| SCHEMBL11024727 | 0.79 | HTT (0.63) | CYP19A1SMN1; SMN2LMNAALDH1A1HTT | |
| SCHEMBL5517557 | 0.79 | CXCR2 (0.50) | SMN1; SMN2LMNAALDH1A1HTTCRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 424 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2158942-A2 | Direct hair dye composition comprising insoluble oxygenated compounds and processes | L'Oreal (FR) | 2010-03-03 | — | — | EP | claimed |
| US-7651534-B2 | Direct dye composition comprising at least one insoluble oxygenated compound, and processes using this composition | L'OREAL SA (FR) | 2010-01-26 | — | — | US | claimed |
| EP-1757326-B1 | Direct dying composition comprising insoluble oxygenated compounds and processes | OREAL (FR) | 2009-01-07 | — | — | EP | claimed |
| US-20070044251-A1 | Direct dye composition comprising at least one insoluble oxygenated compound, and processes using this composition | L'OREAL S.A. (FR) | 2007-03-01 | — | — | US | claimed |
| EP-1757326-A1 | Direct dying composition comprising insoluble oxygenated compounds and processes | L'Oréal (FR) | 2007-02-28 | — | — | EP | claimed |
| EP-1430876-A1 | Composition containing a direct dyestuff and a specific polymer for colouring of keratinic fibres, method for the preparation thereof and process of dyeing with such a composition | L'OREAL (FR) | 2004-06-23 | — | — | EP | claimed |
| EP-4362895-A1 | COMPOSITION COMPRISING PROPANE-1,3-DIOL, AT LEAST ONE ALKANOLAMINE, AT LEAST ONE FATTY SUBSTANCE AND OPTIONALLY AT LEAST ONE POLYOL | L'OREAL (FR) | 2024-05-08 | — | — | EP | disclosed |
| US-11696884-B2 | Compositions comprising menthol compounds as smoothing agents | SYMRISE AG (DE) | 2023-07-11 | — | — | US | disclosed |
| US-11691035-B2 | Oxidizing composition for the treatment of keratin fibers comprising at least one cationic polymer, at least one fatty amide and at least one anti-oxygen agent | L'OREAL (FR) | 2023-07-04 | — | — | US | disclosed |
| US-20230065360-A1 | COSMETIC COMPOSITION COMPRISING A POLYMER COMPRISING AT LEAST ONE CATIONIC (METH)ACRYLAMIDE UNIT, A PARTICULAR SILICONE AND AT LEAST ONE SURFACTANT | L'OREAL (FR) | 2023-03-02 | — | — | US | disclosed |
| WO-2023275207-A1 | COMPOSITION COMPRISING PROPANE-1,3-DIOL, AT LEAST ONE ALKANOLAMINE, AT LEAST ONE FATTY SUBSTANCE AND OPTIONALLY AT LEAST ONE POLYOL | L'OREAL (FR) | 2023-01-05 | — | — | WO | disclosed |
| EP-3389622-B1 | OXIDIZING COMPOSITION FOR TREATING KERATIN MATERIALS, COMPRISING A FATTY SUBSTANCE AND OXYALKYLENATED SURFACTANTS | OREAL (FR) | 2023-01-04 | — | — | EP | disclosed |
| US-11344489-B2 | Azomethine dye chromophores | BASF SE (DE) | 2022-05-31 | — | — | US | disclosed |
| EP-1380820-A1 | Procedure of determining the composition of a dyeing product | L'OREAL S.A. (FR) | 2004-01-14 | — | — | EP | disclosed |
| US-20030152534-A1 | Composition for dyeing keratin fibers comprising a particular aminosilicone | L'OREAL S.A. (FR) | 2003-08-14 | — | — | US | disclosed |
| US-20030140429-A1 | Keratin fibre dyeing composition comprising a particular aminosilicone | L'OREAL S.A. (FR) | 2003-07-31 | — | — | US | disclosed |
| US-20030106169-A1 | Composition for dyeing human keratin fibres, comprising a particular monocationic monoazo dye | L'OREAL S.A. (FR) | 2003-06-12 | — | — | US | disclosed |
| EP-1312344-A2 | Dyeing composition for keratinous fibres containing aminosilicone | L'OREAL (FR) | 2003-05-21 | — | — | EP | disclosed |
| EP-1312343-A2 | Dyeing composition for keratinous fibres containing aminosilicone | L'OREAL S.A. (FR) | 2003-05-21 | — | — | EP | disclosed |
| EP-1297819-A2 | Composition for dyeing keratinous fibres comprising a cationic azo dye | L'OREAL (FR) | 2003-04-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030106169-A1 | Composition for dyeing human keratin fibres, comprising a particular monocationic monoazo dye | KRT18, TUBB3, TUBB1 | CYP19A1 3088/4885SMN1; SMN2 4216/4885LMNA 172/4885 |
| US-11696884-B2 | Compositions comprising menthol compounds as smoothing agents | SMURF1, SMURF2, S1PR2 | CYP19A1 737/4885SMN1; SMN2 1579/4885LMNA 2905/4885 |
| US-11344489-B2 | Azomethine dye chromophores | KRT18, IK, JUP | CYP19A1 1554/4885SMN1; SMN2 4303/4885LMNA 333/4885 |
| US-20230065360-A1 | COSMETIC COMPOSITION COMPRISING A POLYMER COMPRISING AT LEAST ONE CATIONIC (METH)ACRYLAMIDE UNIT, A PARTICULAR SILICONE AND AT LEAST ONE SURFACTANT | KRT18, ACR, MUC1 | CYP19A1 1309/4885SMN1; SMN2 2197/4885LMNA 678/4885 |
| US-20070044251-A1 | Direct dye composition comprising at least one insoluble oxygenated compound, and processes using this composition | KRT18, DSG1, PLOD2 | CYP19A1 890/4885SMN1; SMN2 4784/4885LMNA 1708/4885 |
| US-20030152534-A1 | Composition for dyeing keratin fibers comprising a particular aminosilicone | KRT18, TUBB8, TUBA8 | CYP19A1 1482/4885SMN1; SMN2 4761/4885LMNA 276/4885 |
| US-20030140429-A1 | Keratin fibre dyeing composition comprising a particular aminosilicone | KRT18, TUBB3, TUBA3E | CYP19A1 2127/4885SMN1; SMN2 4685/4885LMNA 1300/4885 |
| US-11691035-B2 | Oxidizing composition for the treatment of keratin fibers comprising at least one cationic polymer, at least one fatty amide and at least one anti-oxygen agent | KRT18, OAT, CUTA | CYP19A1 1054/4885SMN1; SMN2 4607/4885LMNA 1160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.