SCHEMBL616346

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14374109	0.86	ESR1 (0.36)	METKITFGFR1SRCKDR
	SCHEMBL616139	0.86	ESR1 (0.36)	METKITFGFR1SRCKDR
	SCHEMBL616469	0.86	ESR1 (0.43)	METKITFGFR1SRCKDR
	SCHEMBL616913	0.85	ALOX15 (0.46)	METKITFGFR1SRCKDR
	Idronoxil SCHEMBL149612	0.76	ESR2 (0.49)	TYRRARARARGESR1ESR2
	Idronoxil SCHEMBL29353213	0.76	ESR2 (0.49)	TYRRARARARGESR1ESR2
	SCHEMBL677785	0.75	ESR2 (0.42)	TYRRARARARGALOX5ESR1
	SCHEMBL616661	0.73	ESR1 (0.43)	METKITFGFR1SRCKDR
	SCHEMBL21208399	0.72	MET (0.41)	METKITFGFR1SRCKDR
	SCHEMBL26549421	0.71	NISCH (0.48)	RARARARGALOX5ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.