Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10714890 | 0.82 | MAPT (0.49) | KMT2AMEN1MAPTALDH1A1RECQL | |
| SCHEMBL1024700 | 0.81 | MAPT (0.61) | KMT2AMEN1TSHRABCG2MAPT | |
| SCHEMBL19307314 | 0.80 | CA12 (0.35) | KMT2AMAPTALDH1A1RECQLLMNA | |
| SCHEMBL5167952 | 0.80 | MAPT (0.55) | KMT2AMEN1TSHRMAPTALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL27496286 | 0.80 | ABCG2 (0.61) | KMT2AMEN1TSHRABCG2MAPT | |
| SCHEMBL11022003 | 0.80 | MAPT (0.59) | KMT2AMEN1TSHRABCG2MAPT | |
| SCHEMBL28153544 | 0.79 | HDAC3 (0.60) | KMT2AMEN1MAPTALDH1A1RECQL | |
| SCHEMBL16986581 | 0.78 | ALDH1A1 (0.67) | KMT2AMEN1MAPTALDH1A1RECQL | |
| SCHEMBL27650646 | 0.78 | MAPT (0.67) | KMT2AMEN1MAPTALDH1A1RECQL | |
| SCHEMBL195897 | 0.76 | MAPT (0.55) | KMT2AMEN1ABCG2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4935032-A | DIRECT NITROBENZENE DYE | L'OREAL (FR) | 1990-06-19 | — | — | US | claimed |
| US-11324674-B2 | Compositions for neutralizing and coloring hair and methods thereof | STRENGTH OF NATURE, LLC (US) | 2022-05-10 | — | — | US | disclosed |
| US-20150313802-A1 | COMPOSITIONS FOR NEUTRALIZING AND COLORING HAIR AND METHODS THEREOF | STRENGTH OF NATURE, LLC (US) | 2015-11-05 | — | — | US | disclosed |
| US-8950411-B2 | Compositions for neutralizing and coloring hair and methods thereof | STRENGTH OF NATURE, LLC (US) | 2015-02-10 | — | — | US | disclosed |
| US-20130255712-A1 | COMPOSITIONS FOR NEUTRALIZING AND COLORING HAIR AND METHODS THEREOF | STRENGTH OF NATURE, LLC | 2013-10-03 | — | — | US | disclosed |
| US-8256436-B2 | For relaxed hair; mixture of mousse concentrate containing water, acidand surfactant with propellant and coloring agent | STRENGTH OF NATURE, LLC (US) | 2012-09-04 | — | — | US | disclosed |
| US-20050076459-A1 | Compositions for neutralizing and coloring hair and methods thereof | STRENGTH OF NATURE, LLC | 2005-04-14 | — | — | US | disclosed |
| EP-0531738-B2 | Two-pack type keratinous fiber treating composition | KAO CORP (JP) | 2005-02-16 | — | — | EP | disclosed |
| US-6746492-B2 | COMPRISING A DIRECT DYE, A HYDROCARBON OIL AND POLYOXYALKYLENE-MODIFIED DIMETHYL POLYSILOXANE; REDUCED SCALP, SKIN DYEING | KAO CORPORATION (JP) | 2004-06-08 | — | — | US | disclosed |
| US-20020144356-A1 | Comprising a direct dye, a hydrocarbon oil and polyoxyalkylene-modified dimethyl polysiloxane; reduced scalp, skin dyeing | KAO CORPORATION (JP) | 2002-10-10 | — | — | US | disclosed |
| US-5332581-A | Dialkylene glycol monoalkyl ether, aromatic alcohol and weak acid | KAO CORPORATION (JP) | 1994-07-26 | — | — | US | disclosed |
| US-5254333-A | Contains acidic dye, 2-benzyloxyethanol and a water-soluble nonionic polymer; imparts good feeling to hair; safe to hair and skin | KAO CORPORATION (JP) | 1993-10-19 | — | — | US | disclosed |
| EP-0547790-A1 | Dye composition for Keratinous fibers | Kao Corporation (JP) | 1993-06-23 | — | — | EP | disclosed |
| EP-0531738-A2 | Two-pack type keratinous fiber treating composition | KAO CORPORATION (JP) | 1993-03-17 | — | — | EP | disclosed |
| EP-0529598-A1 | Keratinous fiber treating composition | KAO CORPORATION (JP) | 1993-03-03 | — | — | EP | disclosed |
| EP-0503507-A1 | Dye composition for keratinous fibers | Kao Corporation (JP) | 1992-09-16 | — | — | EP | disclosed |
| EP-0470381-A2 | Hair treatment composition and hair dye composition | Kao Corporation (JP) | 1992-02-12 | — | — | EP | disclosed |
| US-4935032-A | DIRECT NITROBENZENE DYE | L'OREAL (FR) | 1990-06-19 | — | — | US | disclosed |
| US-4834768-A | HAIR DYES | L'OREAL (FR) | 1989-05-30 | — | — | US | disclosed |
| US-4637821-A | HAIR, DYEING | L'OREAL (FR) | 1987-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020144356-A1 | Comprising a direct dye, a hydrocarbon oil and polyoxyalkylene-modified dimethyl polysiloxane; reduced scalp, skin dyeing | DECR1, CUTA, POLR1C | KMT2A 660/4885MEN1 1407/4885TSHR 2877/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.