Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7108448 | 0.94 | LMNA (0.53) | LMNAALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL7101534 | 0.94 | LMNA (0.63) | LMNAALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL6165957 | 0.93 | LMNA (0.64) | LMNAALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL6167046 | 0.89 | RORC (0.49) | LMNAALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL20941585 | 0.78 | ALDH1A1 (0.77) | LMNAALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL8639463 | 0.77 | CYP1A2 (0.63) | LMNAALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL6164911 | 0.76 | ADRA2C (0.61) | LMNAADRA2C | |
| SCHEMBL6166508 | 0.74 | ADRA2C (0.56) | LMNAALDH1A1KMT2AMEN1MAPK1 | |
| SCHEMBL6165690 | 0.74 | ADRA2C (0.52) | MAPTSMN1; SMN2ADRA2C | |
| SCHEMBL29767752 | 0.73 | LMNA (1.00) | LMNAALDH1A1KMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1254136-A4 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG CHEM INVESTMENT LTD (KR) | 2005-06-01 | — | — | EP | disclosed |
| EP-1254136-A1 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG Chem Investment, Ltd. (KR) | 2002-11-06 | — | — | EP | disclosed |
| WO-2001055146-A1 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG CHEM INVESTMENT LTD. (KR) | 2001-08-02 | — | — | WO | disclosed |