Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 6/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6165961 | 0.86 | FABP3 (0.48) | HPGDTSHRRECQL | |
| SCHEMBL3775607 | 0.82 | DHODH (0.56) | DHODH | |
| SCHEMBL18224106 | 0.77 | DHODH (0.49) | DHODH | |
| SCHEMBL6163182 | 0.74 | DHODH (0.65) | DHODHALDH1A1TSHR | |
| SCHEMBL18225008 | 0.73 | AR (0.46) | DHODHMAPT | |
| SCHEMBL25134836 | 0.70 | ALDH1A1 (0.77) | ALDH1A1 | |
| SCHEMBL25135076 | 0.70 | ALDH1A1 (0.59) | ALDH1A1 | |
| SCHEMBL25135075 | 0.69 | ALDH1A1 (0.79) | ALDH1A1 | |
| SCHEMBL8557062 | 0.69 | GABRA1 (0.57) | HPGDALDH1A1TSHRRECQLPTK2 | |
| SCHEMBL6166072 | 0.68 | DHODH (0.60) | DHODHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1337523-B1 | 2,4-SUBSTITUTED PYRIDINE DERIVATIVES | NEUROGEN CORP (US) | 2005-10-19 | — | — | EP | claimed |