Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 1/20 | 0.48 |
| ▸ | FABP4 | P15090 | 1/20 | 0.48 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6165007 | 0.86 | DHODH (0.48) | HPGDTSHRRECQL | |
| SCHEMBL3322283 | 0.75 | FABP4 (0.69) | FABP3FABP4FABP5TP53MDM2 | |
| SCHEMBL6163625 | 0.74 | CYP2C9 (0.64) | HPGDLMNATSHR | |
| SCHEMBL8956546 | 0.71 | ALDH1A1 (0.63) | FABP3FABP4FABP5HPGDLMNA | |
| SCHEMBL8557062 | 0.69 | GABRA1 (0.57) | HPGDCNR1TSHRRECQLMEN1 | |
| Acetic Acid SCHEMBL27408297 | 0.68 | PIK3CA (0.55) | FABP3FABP4FABP5 | |
| SCHEMBL23674066 | 0.68 | FABP3 (0.54) | FABP3FABP4FABP5HPGDLMNA | |
| SCHEMBL29980576 | 0.68 | FABP3 (0.54) | FABP3FABP4FABP5HPGDLMNA | |
| SCHEMBL6162171 | 0.68 | POLB (0.58) | HPGDMEN1KMT2A | |
| SCHEMBL3775607 | 0.67 | DHODH (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1337523-B1 | 2,4-SUBSTITUTED PYRIDINE DERIVATIVES | NEUROGEN CORP (US) | 2005-10-19 | — | — | EP | claimed |