Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.40 |
| ▸ | PGK1 | P00558 | 3/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MPI | P34949 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PMM2 | O15305 | 1/20 | 0.36 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | HK1 | P19367 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26287686 | 0.81 | S1PR1 (0.39) | S1PR1PGK1HSP90AA1HSP90AB1ALDH1A1 | |
| SCHEMBL27766866 | 0.77 | HSP90AA1 (0.45) | S1PR1PGK1HSP90AA1HSP90AB1ALDH1A1 | |
| SCHEMBL13313436 | 0.75 | NQO2 (0.46) | S1PR1PGK1HSP90AA1HSP90AB1ALDH1A1 | |
| SCHEMBL21780641 | 0.74 | PGK1 (0.40) | S1PR1PGK1HSP90AA1HSP90AB1ALDH1A1 | |
| SCHEMBL21785001 | 0.74 | PGK1 (0.36) | S1PR1PGK1HSP90AA1HSP90AB1ALDH1A1 | |
| SCHEMBL20241485 | 0.72 | ERN1 (0.43) | PGK1HSP90AA1HSP90AB1ALDH1A1KDM4E | |
| SCHEMBL30682148 | 0.72 | ERN1 (0.43) | PGK1HSP90AA1HSP90AB1ALDH1A1KDM4E | |
| SCHEMBL20241602 | 0.72 | KDM4E (0.44) | PGK1HSP90AA1HSP90AB1ALDH1A1KDM4E | |
| SCHEMBL10639171 | 0.72 | PDE10A (0.34) | ALDH1A1KDM4ESMN1; SMN2GPR35MEN1 | |
| SCHEMBL31396216 | 0.72 | ALDH1A1 (0.39) | ALDH1A1KDM4ESMN1; SMN2GPR35MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11021480-B2 | Inhibiting (α-V)(β-6) integrin | MORPHIC THERAPEUTIC, INC. (US) | 2021-06-01 | — | — | US | disclosed |
| US-20200354359-A1 | INHIBITING (ALPHA-V)(BETA-6) INTEGRIN | MORPHIC THERAPEUTIC, INC. | 2020-11-12 | — | — | US | disclosed |
| EP-1109965-B1 | METHOD OF TREATING A TEXTILE | UNILEVER PLC (GB) | 2005-06-01 | — | — | EP | disclosed |
| EP-1109884-B1 | COMPOSITION AND METHOD FOR BLEACHING A SUBSTRATE | UNILEVER PLC (GB) | 2004-09-01 | — | — | EP | disclosed |
| EP-1433840-A1 | Composition and method for bleaching a substrate | UNILEVER PLC (GB) | 2004-06-30 | — | — | EP | disclosed |
| US-6649582-B1 | Iron 2,11-diaza(3.3)(2,6)pyridinophane derivatives; hydrolytic stability | UNILEVER PATENT HOLDINGS B.V. (NL) | 2003-11-18 | — | — | US | disclosed |
| EP-1087969-B1 | BLEACH CATALYSTS AND FORMULATIONS CONTAINING THEM | UNILEVER PLC (GB) | 2003-04-09 | — | — | EP | disclosed |
| EP-1109965-A1 | METHOD OF TREATING A TEXTILE | UNILEVER PLC (GB) | 2001-06-27 | — | — | EP | disclosed |
| EP-1109884-A1 | COMPOSITION AND METHOD FOR BLEACHING A SUBSTRATE | UNILEVER PLC (GB) | 2001-06-27 | — | — | EP | disclosed |
| US-6245115-B1 | N,N-BIS(PYRIDIN-2-YL-METHYL)-1,1-BIS(PYRIDIN-2-YL)-1-AMINOETHA NE COMPLEX WITH ACETONITRILE AND PERCHLORIC ACID, WHEREBY THE COMPLEX CATALYSES BLEACHING OF THE TEXTILE BY ATMOSPHERIC OXYGEN | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. | 2001-06-12 | — | — | US | disclosed |
| US-6242409-B1 | PERCHLORATE IRON COMPLEX OF ACETONITRILE AND N,N-BIS(PYRIDIN-2-YL-METHYL)-1,1-BIS(PYRIDIN-2-YL)-1-AMINOETHA NE, THE COMPLEX CATALYSING BLEACHING OF A SUBSTRATE BY THE ATMOSPHERIC OXYGEN; PEROXY BLEACH FREE. | UNILEVER HOME & PERSONAL CARE USA | 2001-06-05 | — | — | US | disclosed |
| EP-1087969-A1 | BLEACH CATALYSTS AND FORMULATIONS CONTAINING THEM | UNILEVER PLC (GB) | 2001-04-04 | — | — | EP | disclosed |
| WO-2000012808-A1 | METHOD OF TREATING A TEXTILE | UNILEVER PLC (GB) | 2000-03-09 | — | — | WO | disclosed |
| WO-2000012667-A1 | COMPOSITION AND METHOD FOR BLEACHING A SUBSTRATE | UNILEVER PLC (GB) | 2000-03-09 | — | — | WO | disclosed |
| WO-1999065905-A1 | BLEACH CATALYSTS AND FORMULATIONS CONTAINING THEM | UNILEVER PLC (GB) | 1999-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200354359-A1 | INHIBITING (ALPHA-V)(BETA-6) INTEGRIN | ITGB6, ITGA6, ITGAV | S1PR1 1800/4885PGK1 3100/4885HSP90AA1 854/4885 |
| US-11021480-B2 | Inhibiting (α-V)(β-6) integrin | ITGB6, ITGA6, ITGAV | S1PR1 2007/4885PGK1 3040/4885HSP90AA1 778/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.