SCHEMBL8524609

SCHEMBL8524609

c1ccc(CCc2c[nH]c3ccccc23)cc1

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.70
KMT2A Q03164 2/20 0.70
TRPM8 Q7Z2W7 1/20 0.66
TRPV1 Q8NER1 1/20 0.66
HTR2A P28223 3/20 0.65
CYP3A4 P08684 2/20 0.65
HTR2C P28335 2/20 0.65
MPO P05164 1/20 0.65
CYP1A2 P05177 1/20 0.65
CYP2D6 P10635 1/20 0.65
CYP2A6 P11509 1/20 0.65
NFKB1 P19838 1/20 0.65
HTR1D P28221 1/20 0.65
HTR1B P28222 1/20 0.65
HTR7 P34969 1/20 0.65
CTSK P43235 1/20 0.65
HTR6 P50406 1/20 0.65
CYP2A13 Q16696 1/20 0.65
TAAR1 Q96RJ0 1/20 0.65
PMP22 Q01453 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4985934 0.90 HTR2A (0.77) MEN1KMT2AHTR2ACYP3A4HTR2C
SCHEMBL4788255 0.88 MEN1 (0.56) MEN1KMT2ATRPM8TRPV1HTR2A
SCHEMBL10969880 0.86 GFER (0.65) MEN1KMT2AHTR2ACYP3A4HTR2C
SCHEMBL31060530 0.86 HTR2A (0.57) MEN1KMT2ATRPM8TRPV1HTR2A
SCHEMBL18826588 0.86 KMT2A (0.60) MEN1KMT2AHTR2ACYP3A4HTR2C
SCHEMBL735580 0.86 HTR2A (0.57) MEN1KMT2ATRPM8TRPV1HTR2A
SCHEMBL7263795 0.86 HTR2A (0.57) MEN1KMT2ATRPM8TRPV1HTR2A
SCHEMBL31744670 0.86 HTR2A (0.57) MEN1KMT2AHTR2ACYP3A4HTR2C
SCHEMBL6165432 0.84 MC5R (0.71) MEN1KMT2ATRPM8TRPV1HTR2A
SCHEMBL553605 0.82 MEN1 (1.00) MEN1KMT2ATRPM8TRPV1HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250382268-A1 METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES CFD RES CORPORATION (US) 2025-12-18 US claimed
EP-0890101-A4 SELECTIVELY N-ALKYLATED PEPTIDOMIMETIC COMBINATORIAL LIBRARIES AND COMPOUNDS THEREIN TORREY PINES INST (US) 1999-12-08 EP claimed
EP-0890101-A1 SELECTIVELY N-ALKYLATED PEPTIDOMIMETIC COMBINATORIAL LIBRARIES AND COMPOUNDS THEREIN TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) 1999-01-13 EP claimed
WO-1998033776-A1 COMBINATORIAL LIBRARIES OF HYDANTOIN AND THIOHYDANTOIN DERIVATIVES, METHODS OF MAKING THE LIBRARIES AND COMPOUNDS THEREIN TREGA BIOSCIENCES, INC. (US) 1998-08-06 WO claimed
WO-1997033174-A1 SELECTIVELY N-ALKYLATED PEPTIDOMIMETIC COMBINATORIAL LIBRARIES AND COMPOUNDS THEREIN TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) 1997-09-12 WO claimed
US-4937243-A TREATING CONNECTIVE TISSUE DISEASES BEECHAM GROUP P.L.C. (GB) 1990-06-26 US claimed
US-20250382268-A1 METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES CFD RES CORPORATION (US) 2025-12-18 US disclosed
US-20250382269-A1 METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES CFD RES CORPORATION (US) 2025-12-18 US disclosed
WO-1998033776-A1 COMBINATORIAL LIBRARIES OF HYDANTOIN AND THIOHYDANTOIN DERIVATIVES, METHODS OF MAKING THE LIBRARIES AND COMPOUNDS THEREIN TREGA BIOSCIENCES, INC. (US) 1998-08-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250382269-A1 METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES CD14, MIF, NOD2 MEN1 2402/4885KMT2A 4633/4885TRPM8 2757/4885
US-20250382268-A1 METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES CD14, MIF, NOD2 MEN1 2402/4885KMT2A 4633/4885TRPM8 2757/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.