Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 4/20 | 0.51 |
| ▸ | GBA1 | P04062 | 12/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1001536 | 0.81 | SMPD1 (0.51) | SMPD1GBA1EPHX2 | |
| SCHEMBL23130873 | 0.79 | SMPD1 (0.49) | SMPD1GBA1EPHX2 | |
| SCHEMBL18884734 | 0.78 | GBA1 (0.54) | SMPD1GBA1EPHX2HRH4HRH3 | |
| SCHEMBL19562960 | 0.78 | NR1H4 (0.43) | — | |
| SCHEMBL27424234 | 0.78 | GBA1 (0.54) | SMPD1GBA1EPHX2HRH4HRH3 | |
| SCHEMBL21249256 | 0.76 | SMPD1 (0.56) | SMPD1GBA1EPHX2HRH4HRH3 | |
| SCHEMBL21249259 | 0.76 | SMPD1 (0.56) | SMPD1GBA1EPHX2HRH4HRH3 | |
| SCHEMBL16263567 | 0.74 | SMPD1 (0.54) | SMPD1GBA1HRH4HRH3 | |
| SCHEMBL14289745 | 0.74 | SMPD1 (0.54) | SMPD1GBA1HRH4HRH3 | |
| SCHEMBL6072137 | 0.73 | DPP4 (0.45) | SMPD1GBA1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9657125-B2 | Reactive monomer for a coating and/or reactive coating | ISP INVESTMENTS LLC (US) | 2017-05-23 | — | — | US | claimed |
| US-20120312191-A1 | REACTIVE MONOMER FOR A COATING AND/OR REACTIVE COATING | AVOCA LLC | 2012-12-13 | — | — | US | claimed |
| WO-2011085150-A1 | REACTIVE MONOMER FOR COATING AND/OR REACTIVE COATING | ISP INVESTMENTS INC. (US) | 2011-07-14 | — | — | WO | claimed |
| US-10093633-B2 | Functionalized 4- and 5-vinyl substituted regioisomers of 1, 2, 3-triazoles via 1, 3-dipolar cycloaddition and polymers thereof | ISP INVESTMENTS LLC (US) | 2018-10-09 | — | — | US | disclosed |
| EP-2405757-B1 | FUNCTIONALIZED 4- AND 5-VINYL SUBSTITUTED REGIOISOMERS OF 1,2,3-TRIAZOLES VIA 1,3-DIPOLAR CYCLOADDITION AND POLYMERS THEREOF | ISP INVESTMENTS INC (US) | 2017-11-08 | — | — | EP | disclosed |
| US-9657125-B2 | Reactive monomer for a coating and/or reactive coating | ISP INVESTMENTS LLC (US) | 2017-05-23 | — | — | US | disclosed |
| US-20160083356-A1 | FUNCTIONALIZED 4- AND 5-VINYL SUBSTITUTED REGIOISOMERS OF 1, 2, 3-TRIAZOLES VIA 1, 3- DIPOLAR CYCLOADDITION AND POLYMERS THEREOF | ISP INVESTMENTS INC. (US) | 2016-03-24 | — | — | US | disclosed |
| US-20120312191-A1 | REACTIVE MONOMER FOR A COATING AND/OR REACTIVE COATING | AVOCA LLC | 2012-12-13 | — | — | US | disclosed |
| US-20120041040-A1 | FUNCTIONALIZED 4- AND 5-VINYL SUBSTITUTED REGIOISOMERS OF 1, 2, 3-TRIAZOLES VIA 1, 3-DIPOLAR CYCLOADDITION AND POLYMERS THEREOF | ISP INVESTMENTS INC. (US) | 2012-02-16 | — | — | US | disclosed |
| WO-2011085150-A1 | REACTIVE MONOMER FOR COATING AND/OR REACTIVE COATING | ISP INVESTMENTS INC. (US) | 2011-07-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120041040-A1 | FUNCTIONALIZED 4- AND 5-VINYL SUBSTITUTED REGIOISOMERS OF 1, 2, 3-TRIAZOLES VIA 1, 3-DIPOLAR CYCLOADDITION AND POLYMERS THEREOF | ADH5, ADH1A, ADH1C | SMPD1 4760/4885GBA1 4816/4885EPHX2 1689/4885 |
| US-10093633-B2 | Functionalized 4- and 5-vinyl substituted regioisomers of 1, 2, 3-triazoles via 1, 3-dipolar cycloaddition and polymers thereof | ADH5, ADH1A, ADH1C | SMPD1 4760/4885GBA1 4816/4885EPHX2 1689/4885 |
| US-20120312191-A1 | REACTIVE MONOMER FOR A COATING AND/OR REACTIVE COATING | TH, TET3, PRMT5 | SMPD1 4880/4885GBA1 4836/4885EPHX2 1409/4885 |
| US-20160083356-A1 | FUNCTIONALIZED 4- AND 5-VINYL SUBSTITUTED REGIOISOMERS OF 1, 2, 3-TRIAZOLES VIA 1, 3- DIPOLAR CYCLOADDITION AND POLYMERS THEREOF | ADH5, ADH1A, ADH1C | SMPD1 4760/4885GBA1 4816/4885EPHX2 1689/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.