Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23992 | 0.89 | — | — | |
| SCHEMBL2686745 | 0.89 | — | — | |
| SCHEMBL30487170 | 0.89 | — | — | |
| SCHEMBL11485188 | 0.89 | TSHR (0.33) | TSHR | |
| SCHEMBL2713018 | 0.89 | — | — | |
| Hypochlorous Acid SCHEMBL11413271 | 0.87 | TSHR (0.33) | ALDH1A1TSHR | |
| Chloroform SCHEMBL28128203 | 0.87 | ALDH1A1 (0.31) | ALDH1A1TSHR | |
| Isobutane SCHEMBL3410753 | 0.86 | TSHR (0.31) | TSHR | |
| Ammonia Solution, Strong SCHEMBL2909006 | 0.86 | — | — | |
| Methane SCHEMBL11669299 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6878726-B2 | Pyrazole ether derivatives as anti-inflammatory/analgesic agents | PFIZER INC. (US) | 2005-04-12 | — | — | US | disclosed |
| EP-1233959-B1 | HETEROCYCLO-ALKYLSULFONYL PYRAZOLE DERIVATIVES AS ANTI-INFLAMMATORY/ANALGESIC AGENTS | PFIZER PROD INC (US) | 2005-03-16 | — | — | EP | disclosed |
| US-20050004135-A1 | Pyrazole ether derivatives as anti-inflammatory/analgesic agents | CHENG HENGMAIO (US) | 2005-01-06 | — | — | US | disclosed |
| US-20040259879-A1 | Pyrazole ether derivatives as anti-inflammatory/analgesic agents | CHENG HENGMAIO (US) | 2004-12-23 | — | — | US | disclosed |
| US-20030236258-A1 | Heterocyclo-alkylsulfonyl pyrazole derivatives as anti-inflammatory/analgesic agents | PFIZER INC. | 2003-12-25 | — | — | US | disclosed |
| US-6531492-B1 | Heterocyclo-alkylsulfonyl pyrazole derivatives as anti-inflammatory/analgesic agents | PFIZER INC. | 2003-03-11 | — | — | US | disclosed |
| EP-1259504-A1 | PYRAZOLE ETHER DERIVATIVES AS ANTI-INFLAMMATORY/ANALGESIC AGENTS | Pfizer Products Inc. (US) | 2002-11-27 | — | — | EP | disclosed |
| EP-1233959-A1 | HETEROCYCLO-ALKYLSULFONYL PYRAZOLE DERIVATIVES AS ANTI-INFLAMMATORY/ANALGESIC AGENTS | Pfizer Products Inc. (US) | 2002-08-28 | — | — | EP | disclosed |
| US-20020058681-A1 | Pyrazole ether derivatives as anti-inflammatory/analgesic agents | PFIZER INC. | 2002-05-16 | — | — | US | disclosed |
| WO-2001064669-A1 | PYRAZOLE ETHER DERIVATIVES AS ANTI-INFLAMMATORY/ANALGESIC AGENTS | PFIZER PRODUCTS INC. (US) | 2001-09-07 | — | — | WO | disclosed |
| WO-2001040216-A1 | HETEROCYCLO-ALKYLSULFONYL PYRAZOLE DERIVATIVES AS ANTI-INFLAMMATORY/ANALGESIC AGENTS | PFIZER PRODUCTS INC. (US) | 2001-06-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020058681-A1 | Pyrazole ether derivatives as anti-inflammatory/analgesic agents | PTGER3, PTGER1, P2RX3 | ALDH1A1 386/4885TSHR 2991/4885 |
| US-20030236258-A1 | Heterocyclo-alkylsulfonyl pyrazole derivatives as anti-inflammatory/analgesic agents | PTGS1, SULT2A1, PTGES3 | ALDH1A1 211/4885TSHR 3246/4885 |
| US-20050004135-A1 | Pyrazole ether derivatives as anti-inflammatory/analgesic agents | P2RX3, P2RX7, PTGER3 | ALDH1A1 771/4885TSHR 2015/4885 |
| US-20040259879-A1 | Pyrazole ether derivatives as anti-inflammatory/analgesic agents | PTGER3, PTGER1, P2RX3 | ALDH1A1 386/4885TSHR 2991/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.