SCHEMBL618571

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL619367	0.85	PTGS2 (0.69)	PTGS2PDGFRBPDGFRATUBB4ATUBB
	SCHEMBL616590	0.85	PTGS2 (0.53)	PTGS2PDGFRBPDGFRAALDH1A1LMNA
	SCHEMBL617805	0.83	PTGS2 (0.59)	PTGS2HSD17B10TSHRLMNACASP1
	SCHEMBL616047	0.83	PTGS2 (0.51)	PTGS2PDGFRBPDGFRA
	SCHEMBL616247	0.83	PTGS2 (0.51)	PTGS2TUBB4ATUBBTUBA3CTUBA1B
	SCHEMBL16471418	0.83	PTGS2 (0.51)	PTGS2TUBB4ATUBBTUBA3CTUBA1B
	SCHEMBL617994	0.83	PTGS2 (0.50)	PTGS2PDGFRBPDGFRATUBB4ATUBB
	SCHEMBL618305	0.81	PTGS2 (0.53)	PTGS2PDGFRBPDGFRATUBB4ATUBB
	SCHEMBL617393	0.81	PTGS2 (0.49)	PTGS2TUBB1MEN1KMT2A
	SCHEMBL619458	0.80	PTGS2 (0.51)	PTGS2PDGFRBPDGFRATUBB4ATUBB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.