SCHEMBL617805

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL616590	0.87	PTGS2 (0.53)	PTGS2KITLMNAMAPTSMN1; SMN2
	SCHEMBL619367	0.87	PTGS2 (0.69)	PTGS2LMNA
	SCHEMBL616047	0.86	PTGS2 (0.51)	PTGS2KIT
	SCHEMBL616247	0.86	PTGS2 (0.51)	PTGS2MAPTSMN1; SMN2MAPK1HSD17B10
	SCHEMBL16471418	0.86	PTGS2 (0.51)	PTGS2LMNAPOLBMAPTSMN1; SMN2
	SCHEMBL617994	0.85	PTGS2 (0.50)	PTGS2KITMAPTHSP90AA1HSP90AB1
	SCHEMBL617393	0.83	PTGS2 (0.49)	PTGS2
	SCHEMBL618571	0.83	PTGS2 (0.49)	PTGS2LMNAMAPTTSHRMAPK1
	SCHEMBL14537135	0.82	PTGS2 (0.48)	PTGS2MAPT
	SCHEMBL617559	0.81	PTGS2 (0.54)	PTGS2LMNAMAPTHSD17B10HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.