Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | MMP12 | P39900 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6163711 | 1.00 | TP53 (0.48) | TP53MEN1KMT2AMMEANPEP | |
| SCHEMBL6160300 | 1.00 | TP53 (0.48) | TP53MEN1KMT2AMMEANPEP | |
| SCHEMBL6165543 | 0.85 | MMP12 (0.53) | MMP12PPARGCTSLCTSS | |
| SCHEMBL6160649 | 0.84 | MMP12 (0.50) | KMT2AMMEANPEPMMP12PPARG | |
| SCHEMBL6160645 | 0.84 | MMP12 (0.50) | KMT2AMMEANPEPMMP12PPARG | |
| SCHEMBL6169697 | 0.80 | ROCK2 (0.40) | PPARGCTSLCTSS | |
| SCHEMBL6160891 | 0.80 | PPARG (0.45) | MMEANPEPMMP12PPARG | |
| SCHEMBL6161506 | 0.80 | PPARG (0.45) | MMEANPEPMMP12PPARG | |
| SCHEMBL6161005 | 0.80 | PPARG (0.45) | MMEANPEPMMP12PPARG | |
| SCHEMBL6163224 | 0.78 | ALDH1A1 (0.46) | PPARGCTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0877740-B1 | THIOL DERIVATIVES WITH METALLOPEPTIDASE INHIBITORY ACTIVITY | ZAMBON SPA (IT) | 2005-03-30 | — | — | EP | disclosed |