Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 19/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6166582 | 0.84 | OPRM1 (0.64) | CCNA2CDK2OPRM1OPRK1OPRD1 | |
| SCHEMBL6162652 | 0.83 | CCNA2 (0.45) | CCNA2CDK2OPRM1OPRK1OPRD1 | |
| SCHEMBL6167734 | 0.81 | OPRM1 (0.49) | CCNA2CDK2OPRM1OPRK1OPRD1 | |
| SCHEMBL6163291 | 0.81 | CCNA2 (0.42) | CCNA2CDK2OPRM1 | |
| SCHEMBL6165838 | 0.81 | OPRM1 (0.62) | CCNA2CDK2OPRM1OPRK1OPRD1 | |
| SCHEMBL6165095 | 0.80 | ALDH1A1 (0.58) | CCNA2CDK2OPRM1OPRK1OPRD1 | |
| SCHEMBL6168412 | 0.79 | CCNA2 (0.40) | CCNA2CDK2 | |
| SCHEMBL6164838 | 0.78 | CCNA2 (0.41) | CCNA2CDK2OPRM1OPRK1OPRD1 | |
| SCHEMBL6165262 | 0.78 | CCNA2 (0.40) | CCNA2CDK2 | |
| SCHEMBL6767006 | 0.78 | OPRM1 (0.58) | OPRM1OPRK1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1177185-B1 | 4, 5, 6, 7-TETRAHYDROINDAZOLE DERIVATIVES AS ANTITUMOR AGENTS | PHARMACIA ITALIA SPA (IT) | 2005-04-20 | — | — | EP | disclosed |
| US-6716856-B1 | CELL PROLIFERATIVE DISORDERS OR ALZHEIMER'S DISEASE; REDUCED TOXICITY; CDK/CYCLIN KINASE INHIBITORY ACTIVITY | PHARMACIA & TUBJOHN SPA (IT) | 2004-04-06 | — | — | US | disclosed |