Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMO | Q99835 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6167465 | 0.86 | L3MBTL1 (0.47) | CNR1ALDH1A1MAPTALOX12HPGD | |
| SCHEMBL7481341 | 0.79 | CNR1 (0.55) | CNR1ALDH1A1MAPTGAAELANE | |
| SCHEMBL6168238 | 0.77 | NPC1 (0.51) | ALDH1A1SMN1; SMN2GAAMEN1KMT2A | |
| SCHEMBL6628115 | 0.77 | CNR1 (0.49) | CNR1ALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL6167711 | 0.74 | CNR1 (0.50) | CNR1ALDH1A1GAALMNA | |
| SCHEMBL6625012 | 0.73 | CNR1 (0.46) | CNR1ALDH1A1MAPTALOX12HPGD | |
| SCHEMBL6168870 | 0.73 | GAA (0.46) | CNR1ALDH1A1MAPTSMN1; SMN2GAA | |
| SCHEMBL6624582 | 0.72 | CNR1 (0.45) | CNR1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6169738 | 0.72 | CNR1 (0.43) | CNR1ALDH1A1GAAKDM4EMEN1 | |
| SCHEMBL6625246 | 0.71 | HTT (0.49) | CNR1ALDH1A1MAPTALOX12SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546111-A2 | 2-THIOHYDANTOINE DERIVATIVE COMPOUNDS AND USE THEREOF FOR THE TREATMENT OF DIABETES | LABORATOIRES FOURNIER S.A. (FR) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004031160-A2 | 2-THIOHYDANTOINE DERIVATIVE COMPOUNDS AND USE THEREOF FOR THE TREATMENT OF DIABETES | LABORATOIRES FOURNIER S.A. (FR) | 2004-04-15 | — | — | WO | disclosed |