Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 10/20 | 0.50 |
| ▸ | RAB9A | P51151 | 9/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | ALPL | P05186 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ALPI | P09923 | 1/20 | 0.48 |
| ▸ | ALPG | P10696 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 8/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.47 |
| ▸ | HPGD | P15428 | 7/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.47 |
| ▸ | PKM | P14618 | 3/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2465146 | 0.81 | RAB9A (0.45) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL2465148 | 0.78 | RAB9A (0.42) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL824375 | 0.74 | NPC1 (0.69) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL29531707 | 0.74 | NPC1 (0.69) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL13522921 | 0.73 | NPC1 (0.54) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL31631311 | 0.73 | NPC1 (0.64) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL21674120 | 0.72 | NPC1 (0.61) | NPC1RAB9AMEN1KMT2AATM | |
| Anthracene SCHEMBL29003509 | 0.70 | NPC1 (0.66) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL12861182 | 0.70 | PTGS2 (0.60) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL2381205 | 0.70 | ATM (0.61) | NPC1RAB9AMEN1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1414814-B1 | 6-ARYL-4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2005-02-02 | — | — | EP | disclosed |
| US-6784137-B2 | SUCH AS 5,6-DICHLOROPYRIDINE-2-CARBOXYLIC ACID-N-OXIDE FOR PREEMERGENCE APPLICATION | DOW AGROSCIENCES LLC | 2004-08-31 | — | — | US | disclosed |
| EP-1414814-A1 | 6-ARYL-4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES | Dow Agrosciences LLC (US) | 2004-05-06 | — | — | EP | disclosed |
| US-20030114311-A1 | 6-Aryl-4-aminopicolinates and their use as herbicides | CORTEVA AGRISCIENCE LLC | 2003-06-19 | — | — | US | disclosed |
| WO-2003011853-A1 | 6-ARYL-4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2003-02-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030114311-A1 | 6-Aryl-4-aminopicolinates and their use as herbicides | AADAC, DDT, AADAT | NPC1 3789/4885RAB9A 2477/4885MEN1 4459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.