Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6165859 | 0.72 | — | — | |
| SCHEMBL6168602 | 0.68 | SMN1; SMN2 (0.56) | POLBSMN1; SMN2LMNAALDH1A1KDM4E | |
| SCHEMBL6167149 | 0.66 | ALOX15 (0.31) | — | |
| SCHEMBL10288508 | 0.60 | ALDH1A1 (0.53) | ALDH1A3POLBLMNAALDH1A1KDM4E | |
| SCHEMBL2806281 | 0.57 | ALDH1A3 (0.49) | ALDH1A3SMN1; SMN2LMNAALDH1A1KDM4E | |
| SCHEMBL10133331 | 0.57 | TRIM24 (0.57) | SMN1; SMN2LMNAALDH1A1KDM4EMEN1 | |
| SCHEMBL28825916 | 0.57 | SMN1; SMN2 (0.52) | POLBSMN1; SMN2ALDH1A1RECQLNPC1 | |
| SCHEMBL17805419 | 0.57 | ALDH1A1 (0.50) | POLBSMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL28272953 | 0.57 | ALDH1A1 (0.42) | LMNAALDH1A1 | |
| SCHEMBL10987001 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1498109-A1 | Furan derivatives and dyeing composition comprising a furan derivative as coupler | L'OREAL (FR) | 2005-01-19 | — | — | EP | claimed |
| EP-1498109-A1 | Furan derivatives and dyeing composition comprising a furan derivative as coupler | L'OREAL (FR) | 2005-01-19 | — | — | EP | disclosed |