Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.49 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.47 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1250428 | 0.83 | ALDH3A1 (0.53) | ALDH1A3ALDH1A1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL4938336 | 0.83 | ADRB1 (0.61) | ALDH1A1KDM4ELMNACHRM2CHRM4 | |
| SCHEMBL9694007 | 0.81 | ALDH1A1 (0.48) | ALDH1A3ALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL9830754 | 0.76 | IP6K1 (0.45) | ALDH1A3ALDH1A1SMN1; SMN2KDM4EIP6K1 | |
| SCHEMBL18297686 | 0.76 | ALDH1A1 (0.47) | ALDH1A3TRIM24TRIM33ALDH1A1SMN1; SMN2 | |
| SCHEMBL15093843 | 0.76 | ALDH1A1 (0.59) | ALDH1A3TRIM24TRIM33ALDH1A1SMN1; SMN2 | |
| SCHEMBL20556701 | 0.74 | TRIM24 (0.55) | ALDH1A3TRIM24TRIM33ALDH1A1SMN1; SMN2 | |
| SCHEMBL23932966 | 0.74 | ALDH1A1 (0.58) | ALDH1A3TRIM24TRIM33ALDH1A1SMN1; SMN2 | |
| SCHEMBL2273801 | 0.73 | ADRB1 (0.58) | TRIM24TRIM33ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL9829419 | 0.73 | ADRB1 (0.64) | TRIM24TRIM33ALDH1A1SMN1; SMN2IP6K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118367-A2 | ANTIVIRAL PYRIMIDINES | PROGENICS PHARMACEUTICALS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |