Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | NISCH | Q9Y2I1 | 5/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2790488 | 0.79 | CYP2D6 (0.44) | ADRA2AADRA1AADRA1DADRA1BHTR2A | |
| SCHEMBL2776285 | 0.74 | ADRA1A (0.54) | ADRA2AADRA1AADRA1DADRA1BHTR2A | |
| SCHEMBL10851796 | 0.68 | ADRA2A (0.41) | ADRA2AADRA1AADRA1DADRA1BMAOA | |
| SCHEMBL20232167 | 0.66 | HTR2A (0.65) | HTR2AMAOAMAPT | |
| SCHEMBL2777913 | 0.66 | ADRA2A (0.41) | ADRA2AADRA1AADRA1DADRA1BNISCH | |
| Hydrochloric Acid SCHEMBL10749865 | 0.66 | CYP2D6 (0.59) | ADRA2AADRA1AMAOAALDH1A1HTR1A | |
| SCHEMBL17014922 | 0.65 | CYP3A4 (0.43) | MAOAALDH1A1MAPTCYP2D6 | |
| SCHEMBL6174277 | 0.64 | MAPT (0.46) | HTR2AMAOAKDM4EALDH1A1GAA | |
| SCHEMBL361694 | 0.64 | MAPT (0.46) | HTR2AMAOAKDM4EALDH1A1GAA | |
| SCHEMBL9814124 | 0.63 | ADRA1A (0.53) | ADRA2AADRA1AMAOAALDH1A1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1499609-A4 | PESTICIDAL HETEROCYCLES | FMC CORP (US) | 2005-09-14 | — | — | EP | disclosed |
| EP-1499609-A2 | PESTICIDAL HETEROCYCLES | FMC CORPORATION (US) | 2005-01-26 | — | — | EP | disclosed |
| WO-2003092374-A2 | PESTICIDAL HETEROCYCLES | FMC CORPORATION (US) | 2003-11-13 | — | — | WO | disclosed |