Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.57 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.57 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | NOS1 | P29475 | 1/20 | 0.51 |
| ▸ | PLAU | P00749 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 7/20 | 0.49 |
| ▸ | NPC1 | O15118 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.49 |
| ▸ | RELA | Q04206 | 2/20 | 0.49 |
| ▸ | GFER | P55789 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4704845 | 0.94 | LTA4H (0.59) | LTA4HMKNK1MKNK2ALDH1A1MAPT | |
| SCHEMBL10242015 | 0.80 | GAA (0.78) | ALDH1A1MAPTKDM4EPOLBGAA | |
| SCHEMBL7236001 | 0.79 | ALDH1A1 (0.59) | LTA4HMKNK1MKNK2ALDH1A1MAPT | |
| SCHEMBL29276767 | 0.79 | ALDH1A1 (0.67) | LTA4HMKNK1MKNK2ALDH1A1MAPT | |
| SCHEMBL2762257 | 0.75 | MPL (0.63) | LTA4HMKNK1MKNK2ALDH1A1MAPT | |
| SCHEMBL10200395 | 0.75 | LTA4H (0.59) | LTA4HMKNK1MKNK2ALDH1A1MAPT | |
| SCHEMBL10315917 | 0.75 | LTA4H (0.59) | LTA4HMKNK1MKNK2ALDH1A1MAPT | |
| SCHEMBL10315892 | 0.75 | LTA4H (0.59) | LTA4HMKNK1MKNK2ALDH1A1MAPT | |
| SCHEMBL16346609 | 0.75 | RAB9A (0.57) | LTA4HMKNK1MKNK2ALDH1A1MAPT | |
| SCHEMBL127798 | 0.75 | ABL1 (0.58) | LTA4HMKNK1MKNK2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506195-A2 | NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | Boehringer Ingelheim International GmbH (DE) | 2005-02-16 | — | — | EP | disclosed |
| WO-2003097644-A2 | NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2003-11-27 | — | — | WO | disclosed |