Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27683380 | 0.84 | DYRK1A (0.34) | DYRK1AMAPK1MAPTGAAALDH1A1 | |
| SCHEMBL9978669 | 0.82 | SMN1; SMN2 (0.33) | MEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL28802178 | 0.80 | MAPT (0.36) | MEN1KMT2AKDM4EMAPK1MAPT | |
| SCHEMBL627520 | 0.74 | MAPK1 (0.57) | POLBMAPK1MAPTHTTGAA | |
| SCHEMBL15728491 | 0.70 | KMT2A (0.47) | MEN1KMT2APOLBKDM4EMAPK1 | |
| SCHEMBL7097302 | 0.69 | LMNA (0.36) | MEN1KMT2APOLBMAPTGAA | |
| SCHEMBL12332643 | 0.68 | SMN1; SMN2 (0.37) | DYRK1AMEN1KMT2APOLBKDM4E | |
| SCHEMBL14917715 | 0.67 | MAPK1 (0.34) | DYRK1AKMT2AMAPK1MAPTHTT | |
| SCHEMBL10399828 | 0.66 | — | — | |
| SCHEMBL2427435 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1503990-A1 | ACTIVE SUBSTANCES FOR THE TREATMENT, DIAGNOSIS AND PROPHYLAXIS OF DISEASES IN WHICH ABNORMAL PROTEIN STRUCTURES OCCUR | Transmit Gesellschaft für Technologietransfer mbH (DE) | 2005-02-09 | — | — | EP | disclosed |
| WO-2003095429-A1 | ACTIVE SUBSTANCES FOR THE TREATMENT, DIAGNOSIS AND PROPHYLAXIS OF DISEASES IN WHICH ABNORMAL PROTEIN STRUCTURES OCCUR | TransMIT Gesellschaft für Technologietransfer mbH (DE) | 2003-11-20 | — | — | WO | disclosed |