Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.47 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CHKA | P35790 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 2/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TERT | O14746 | 1/20 | 0.36 |
| ▸ | S100B | P04271 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6167874 | 1.00 | HRH4 (0.47) | HRH4ELOVL1MAPTALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL7260368 | 0.99 | HRH4 (0.46) | HRH4ELOVL1MAPTALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL7260366 | 0.99 | HRH4 (0.46) | HRH4ELOVL1MAPTALDH1A1LMNA | |
| SCHEMBL25813337 | 0.73 | HRH4 (0.47) | HRH4ELOVL1MAPTALDH1A1CHKA | |
| SCHEMBL8683198 | 0.72 | RRM2 (0.43) | HRH4KDM4E | |
| SCHEMBL9455784 | 0.70 | HRH4 (0.58) | HRH4ELOVL1MAPTALDH1A1LMNA | |
| SCHEMBL425041 | 0.68 | HRH4 (0.56) | HRH4ELOVL1MAPTALDH1A1MAPK1 | |
| SCHEMBL17256990 | 0.67 | KDM4E (0.37) | ALDH1A1LMNAKDM4E | |
| SCHEMBL5847761 | 0.66 | HRH4 (0.54) | HRH4ELOVL1MAPTALDH1A1LMNA | |
| SCHEMBL31341814 | 0.66 | HRH4 (0.54) | HRH4ELOVL1MAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1177189-B1 | SOLVATES OF PYMETROZINE | SYNGENTA PARTICIPATIONS AG (CH) | 2005-12-14 | — | — | EP | disclosed |
| US-6784176-B2 | SOLVENTS AND HYDRATES OF PYMETROZINE OR ITS SALTS USED FOR THE CONTROL OF PESTS. | SYNGENTA CROP PROTECTION, INC. | 2004-08-31 | — | — | US | disclosed |
| CN-1350529-A | Solvates of pymetrozine | SHINGENTA INC (CH) | 2002-05-22 | — | — | CN | disclosed |
| EP-1177189-A2 | SOLVATES OF PYMETROZINE | Syngenta Participations AG (CH) | 2002-02-06 | — | — | EP | disclosed |
| WO-2000068222-A2 | SOLVATES OF PYMETROZINE | SYNGENTA PARTICIPATIONS AG (CH) | 2000-11-16 | — | — | WO | disclosed |