Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.47 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CHKA | P35790 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 2/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TERT | O14746 | 1/20 | 0.36 |
| ▸ | S100B | P04271 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6167866 | 1.00 | HRH4 (0.47) | HRH4ELOVL1MAPTALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL7260368 | 0.99 | HRH4 (0.46) | HRH4ELOVL1MAPTALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL7260366 | 0.99 | HRH4 (0.46) | HRH4ELOVL1MAPTALDH1A1LMNA | |
| SCHEMBL25813337 | 0.73 | HRH4 (0.47) | HRH4ELOVL1MAPTALDH1A1CHKA | |
| SCHEMBL8683198 | 0.72 | RRM2 (0.43) | HRH4KDM4E | |
| SCHEMBL9455784 | 0.70 | HRH4 (0.58) | HRH4ELOVL1MAPTALDH1A1LMNA | |
| SCHEMBL425041 | 0.68 | HRH4 (0.56) | HRH4ELOVL1MAPTALDH1A1MAPK1 | |
| SCHEMBL17256990 | 0.67 | KDM4E (0.37) | ALDH1A1LMNAKDM4E | |
| SCHEMBL5847761 | 0.66 | HRH4 (0.54) | HRH4ELOVL1MAPTALDH1A1LMNA | |
| SCHEMBL31341814 | 0.66 | HRH4 (0.54) | HRH4ELOVL1MAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1436282-B1 | SYNTHESIS OF 4-(PIPERIDYL) (2-PYRIDYL)METHANONE-(E)-O-METHYLOXIME AND ITS SALTS | SCHERING CORP (US) | 2005-06-22 | — | — | EP | disclosed |
| US-6642385-B2 | Producing high purity stereoisomer; forming grignard derivative of 4-halo-piperidine carbamate and coupling with 2-cyanopyridine; oximination with alkyl chloroformate; hydrolyzing to free base | SCHERING CORPORATION | 2003-11-04 | — | — | US | disclosed |
| US-6642385-B2 | Producing high purity stereoisomer; forming grignard derivative of 4-halo-piperidine carbamate and coupling with 2-cyanopyridine; oximination with alkyl chloroformate; hydrolyzing to free base | SCHERING CORPORATION | 2003-11-04 | — | — | US | disclosed |
| US-20030105136-A1 | Synthesis of 4-(piperidyl)(2-pyridyl)methanone-(E)-O-methyloxime and salts | SCHERING CORPORATION | 2003-06-05 | — | — | US | disclosed |
| US-20030105136-A1 | Synthesis of 4-(piperidyl)(2-pyridyl)methanone-(E)-O-methyloxime and salts | SCHERING CORPORATION | 2003-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030105136-A1 | Synthesis of 4-(piperidyl)(2-pyridyl)methanone-(E)-O-methyloxime and salts | DNMT1, PAM, TET2 | HRH4 305/4885ELOVL1 3322/4885MAPT 3873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.