Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 20/20 | 0.59 |
| ▸ | GABRD | O14764 | 20/20 | 0.59 |
| ▸ | GABRA1 | P14867 | 20/20 | 0.59 |
| ▸ | GABRB1 | P18505 | 20/20 | 0.59 |
| ▸ | GABRG2 | P18507 | 20/20 | 0.59 |
| ▸ | GABRB3 | P28472 | 20/20 | 0.59 |
| ▸ | GABRA5 | P31644 | 20/20 | 0.59 |
| ▸ | GABRA3 | P34903 | 20/20 | 0.59 |
| ▸ | GABRA2 | P47869 | 20/20 | 0.59 |
| ▸ | GABRB2 | P47870 | 20/20 | 0.59 |
| ▸ | GABRA4 | P48169 | 20/20 | 0.59 |
| ▸ | GABRE | P78334 | 20/20 | 0.59 |
| ▸ | GABRA6 | Q16445 | 20/20 | 0.59 |
| ▸ | GABRG1 | Q8N1C3 | 20/20 | 0.59 |
| ▸ | GABRG3 | Q99928 | 20/20 | 0.59 |
| ▸ | GABRQ | Q9UN88 | 20/20 | 0.59 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6055912 | 0.93 | GABRP (0.59) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6169732 | 0.91 | GABRP (0.50) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL15406 | 0.91 | GABRP (0.61) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6055611 | 0.91 | GABRP (0.61) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6055655 | 0.89 | GABRP (0.60) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL2837760 | 0.89 | GABRP (0.60) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9430248 | 0.89 | GABRP (0.60) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9342873 | 0.88 | GABRP (0.59) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6055668 | 0.88 | GABRP (0.59) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6055669 | 0.88 | GABRP (0.67) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE37495-E1 | Substituted 1-arylpyrazoles | BAYER AKTIENGESELLSCHAFT (DE) | 2002-01-01 | — | — | US | claimed |
| US-5580843-A | INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-12-03 | — | — | US | claimed |
| US-9609871-B2 | Combination product for controlling parasites on animals | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2017-04-04 | — | — | US | disclosed |
| US-9609871-B2 | Combination product for controlling parasites on animals | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2017-04-04 | — | — | US | disclosed |
| EP-2104426-B1 | AGENTS FOR CONTROLLING PARASITES ON ANIMALS | BAYER IP GMBH (DE) | 2016-03-30 | — | — | EP | disclosed |
| US-20160007611-A1 | Combination product for controlling parasites on animals | ELANCO ANIMAL HEALTH GMBH (DE) | 2016-01-14 | — | — | US | disclosed |
| US-20160007611-A1 | Combination product for controlling parasites on animals | ELANCO ANIMAL HEALTH GMBH (DE) | 2016-01-14 | — | — | US | disclosed |
| EP-2104428-B1 | COMBINATION PRODUCT FOR CONTROLLING PARASITES ON ANIMALS | BAYER IP GMBH (DE) | 2015-10-14 | — | — | EP | disclosed |
| US-9137995-B2 | Combination product for controlling parasites on animals | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-09-22 | — | — | US | disclosed |
| US-9137995-B2 | Combination product for controlling parasites on animals | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-09-22 | — | — | US | disclosed |
| US-20130045996-A1 | COMBINATION PRODUCT FOR CONTROLLING PARASITES ON ANIMALS | BAYER ANIMAL HEALTH GMBH (DE) | 2013-02-21 | — | — | US | disclosed |
| EP-0659745-B1 | Substituted 1-aryl pyrazoles | BAYER CROPSCIENCE AG (DE) | 2005-07-27 | — | — | EP | disclosed |
| EP-0942904-B1 | 3-THIOCARBAMOYLPYRAZOLE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2004-06-23 | — | — | EP | disclosed |
| US-RE37495-E1 | Substituted 1-arylpyrazoles | BAYER AKTIENGESELLSCHAFT (DE) | 2002-01-01 | — | — | US | disclosed |
| US-6265430-B1 | INSECTICIDES, MITICIDES, NEMATOCIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-07-24 | — | — | US | disclosed |
| US-20010007876-A1 | 3-THIOCARBAMOYLPYRAZOLE DERIVATIVES AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-07-12 | — | — | US | disclosed |
| EP-0942904-A1 | 3-THIOCARBAMOYLPYRAZOLE DERIVATIVES AS PESTICIDES | BAYER AG (DE) | 1999-09-22 | — | — | EP | disclosed |
| WO-1998024769-A1 | 3-THIOCARBAMOYLPYRAZOLE DERIVATIVES AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-06-11 | — | — | WO | disclosed |
| US-5580843-A | INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-12-03 | — | — | US | disclosed |
| EP-0659745-A1 | Substituted 1-aryl pyrazoles | BAYER AG (DE) | 1995-06-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160007611-A1 | Combination product for controlling parasites on animals | CYCS, CYP3A43, CDIPT | GABRP 68/4885GABRD 346/4885GABRA1 385/4885 |
| US-20130045996-A1 | COMBINATION PRODUCT FOR CONTROLLING PARASITES ON ANIMALS | CYCS, CYP3A43, CDIPT | GABRP 68/4885GABRD 346/4885GABRA1 385/4885 |
| US-20010007876-A1 | 3-THIOCARBAMOYLPYRAZOLE DERIVATIVES AS PESTICIDES | NCS1, CYP1B1, DDT | GABRP 1580/4885GABRD 3170/4885GABRA1 2053/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.