Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GPR183 | P32249 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.37 |
| ▸ | PRKCI | P41743 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | RYR2 | Q92736 | 1/20 | 0.35 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7818520 | 0.84 | PRKCI (0.40) | GSK3BNPC1RAB9APKMPRKCI | |
| SCHEMBL7817042 | 0.82 | ERN1 (0.39) | MEN1KMT2AGSK3BNPC1RAB9A | |
| SCHEMBL10106909 | 0.81 | ALDH1A1 (0.45) | MEN1KMT2ANPC1RAB9APKM | |
| SCHEMBL8978552 | 0.78 | TDP1 (0.41) | NPC1RAB9ATP53SMN1; SMN2KDM4E | |
| SCHEMBL25954061 | 0.78 | ELANE (0.46) | SMN1; SMN2MAPTALDH1A1LMNACA12 | |
| SCHEMBL164160 | 0.78 | ELANE (0.46) | SMN1; SMN2MAPTALDH1A1LMNACA12 | |
| SCHEMBL7807844 | 0.76 | PRKCI (0.38) | NPC1RAB9APKMPRKCIERN1 | |
| SCHEMBL6400299 | 0.76 | CA12 (0.47) | NPC1RAB9ATP53SMN1; SMN2MAPT | |
| SCHEMBL25954066 | 0.75 | ELANE (0.40) | KMT2ANPC1RAB9ATP53PKM | |
| SCHEMBL3716710 | 0.74 | GSK3B (0.48) | MEN1KMT2AGPR183GSK3BNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792468-B2 | NOVEL PHOTOCHROMIC INDENO-FUSED NAPHTHOPYRANS | PPG IND OHIO INC (US) | 2005-05-04 | — | — | EP | disclosed |
| EP-0792468-B1 | NOVEL PHOTOCHROMIC INDENO-FUSED NAPHTHOPYRANS | PPG IND OHIO INC (US) | 2002-04-03 | — | — | EP | disclosed |
| EP-0801750-B1 | NOVEL SUBSTITUTED PHENANTHROPYRANS | PPG IND OHIO INC (US) | 2001-11-07 | — | — | EP | disclosed |
| EP-0801750-A4 | NOVEL SUBSTITUTED PHENANTHROPYRANS | PPG INDUSTRIES INC (US) | 1997-12-10 | — | — | EP | disclosed |
| EP-0801750-A1 | NOVEL SUBSTITUTED PHENANTHROPYRANS | PPG INDUSTRIES, INC. (US) | 1997-10-22 | — | — | EP | disclosed |
| US-5656206-A | OPHTHALIMIC LENSES; RADIATION TRANSPARENT; PHOTOCHROMISM | TRANSITIONS OPTICAL, INC. (US) | 1997-08-12 | — | — | US | disclosed |
| US-5645767-A | PLASTIC LENSES, WINDOWS, BATHOCHROMIC SHIFT FOR WAVELENGTHS IN VISIBLE SPECTRUM | TRANSITIONS OPTICAL, INC. (US) | 1997-07-08 | — | — | US | disclosed |
| US-5573712-A | PHOTOCHROMIC ARTICLE COMPRISING ORGANIC HOST AND THE PHOTOCHROMIC NAPHTHOPYRAN | TRANSITIONS OPTICAL, INC. (US) | 1996-11-12 | — | — | US | disclosed |
| WO-1996014596-A1 | NOVEL PHOTOCHROMIC INDENO-FUSED NAPHTHOPYRANS | PPG INDUSTRIES, INC. (US) | 1996-05-17 | — | — | WO | disclosed |
| US-5514817-A | PHOTOCHROMIC | PPG INDUSTRIES, INC. (US) | 1996-05-07 | — | — | US | disclosed |
| WO-1996004576-A1 | NOVEL SUBSTITUTED PHENANTHROPYRANS | PPG INDUSTRIES, INC. (US) | 1996-02-15 | — | — | WO | disclosed |
| US-5458814-A | Ophthalmic lenses | TRANSITIONS OPTICAL, INC. (US) | 1995-10-17 | — | — | US | disclosed |
| WO-1995016215-A1 | NOVEL SUBSTITUTED NAPHTHOPYRANS | PPG INDUSTRIES, INC. (US) | 1995-06-15 | — | — | WO | disclosed |