Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.42 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.42 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.42 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.42 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30730695 | 0.92 | CASP1 (0.44) | CA12CA1CA2CA7CA9 | |
| SCHEMBL10102361 | 0.88 | ACHE (0.47) | CA12CA1CA2CA7CA9 | |
| SCHEMBL25954061 | 0.87 | ELANE (0.46) | CA12CA1CA2CA7CA9 | |
| SCHEMBL164160 | 0.87 | ELANE (0.46) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8132623 | 0.85 | CA12 (0.50) | CA12CA1CA2CA7CA9 | |
| SCHEMBL29149576 | 0.84 | PDE4A (0.41) | ALDH1A1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL25954066 | 0.84 | ELANE (0.40) | CA12CA1CA2CA7CA9 | |
| SCHEMBL25954058 | 0.82 | LTA4H (0.48) | CA12CA1CA2CA7CA9 | |
| SCHEMBL25954108 | 0.82 | LTA4H (0.48) | CA12CA1CA2CA7CA9 | |
| SCHEMBL25954105 | 0.82 | ESR2 (0.48) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050258408-A1 | Photochromic contact lenses and methods for their production | MOLOCK FRANK F | 2005-11-24 | — | — | US | disclosed |
| EP-0920645-B1 | NAPHTHOPYRANS, COMPOSITIONS AND ARTICLES CONTAINING THEM | CORNING INC (US) | 2002-04-03 | — | — | EP | disclosed |
| EP-0920645-A4 | NAPHTHOPYRANS, COMPOSITIONS AND ARTICLES CONTAINING THEM | CORNING INC (US) | 1999-08-25 | — | — | EP | disclosed |
| EP-0920645-A1 | NAPHTHOPYRANS, COMPOSITIONS AND ARTICLES CONTAINING THEM | CORNING INCORPORATED (US) | 1999-06-09 | — | — | EP | disclosed |
| WO-1998004937-A1 | NAPHTHOPYRANS, COMPOSITIONS AND ARTICLES CONTAINING THEM | CORNING INCORPORATED (US) | 1998-02-05 | — | — | WO | disclosed |
| WO-1994020869-A1 | NOVEL BENZOPYRANS | PPG INDUSTRIES, INC. (US) | 1994-09-15 | — | — | WO | disclosed |