SCHEMBL6168670

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6169290	0.90	KCNK3 (0.42)	EGFRITKMAPTSMN1; SMN2PTPN11
	SCHEMBL6168126	0.88	PTPN11 (0.43)	EGFRITKMAPTPTPN11SCN3A
	SCHEMBL6167971	0.85	RAB9A (0.52)	EGFRITKMAPTSMN1; SMN2ALDH1A1
	SCHEMBL6171890	0.85	MEN1 (0.50)	EGFRITKSMN1; SMN2ALDH1A1NPC1
	SCHEMBL6170175	0.83	TP53 (0.51)	EGFRITKMAPTSMN1; SMN2NPC1
	SCHEMBL28087693	0.82	EGFR (0.46)	EGFRITKNOTUMROCK2ROCK1
	SCHEMBL6171299	0.81	HTT (0.51)	MAPTSMN1; SMN2ALDH1A1RAB9ATHRB
	SCHEMBL6171464	0.80	RAB9A (0.48)	EGFRITKMAPTSMN1; SMN2ALDH1A1
	SCHEMBL6169372	0.79	NR1H4 (0.56)	MAPTSMN1; SMN2THRBRXFP1TP53
	SCHEMBL6170962	0.77	NPC1 (0.53)	NPC1RAB9ARXFP1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.