SCHEMBL6171464

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6167971	0.91	RAB9A (0.52)	RAB9ASMN1; SMN2KMT2AMEN1ALDH1A1
	SCHEMBL6169290	0.88	KCNK3 (0.42)	RAB9ASMN1; SMN2KMT2AMEN1MAPT
	SCHEMBL6171299	0.85	HTT (0.51)	RAB9ASMN1; SMN2KMT2AMEN1ALDH1A1
	SCHEMBL6168824	0.81	NR1H4 (0.48)	SMN1; SMN2KMT2AMEN1MAPTKCNK3
	SCHEMBL6171890	0.80	MEN1 (0.50)	RAB9ASMN1; SMN2KMT2AMEN1ALDH1A1
	SCHEMBL6168670	0.80	EGFR (0.43)	RAB9ASMN1; SMN2KMT2AMEN1ALDH1A1
	SCHEMBL6168126	0.80	PTPN11 (0.43)	RAB9AMAPTEGFRITKNPC1
	SCHEMBL6170962	0.77	NPC1 (0.53)	RAB9AKMT2AMEN1POLBNPC1
	SCHEMBL6169267	0.76	TP53 (0.43)	SMN1; SMN2KMT2AMEN1MAPTBRPF1
	SCHEMBL28087693	0.75	EGFR (0.46)	EGFRITKNOTUM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.