Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 3/20 | 0.35 |
| ▸ | MMP3 | P08254 | 2/20 | 0.35 |
| ▸ | MMP9 | P14780 | 2/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP7 | P09237 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | P2RY12 | Q9H244 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3631919 | 0.81 | ALDH1A1 (0.35) | LMNASMN1; SMN2TSHRGAAALDH1A1 | |
| SCHEMBL427722 | 0.81 | EPHX1 (0.38) | HPGDALDH1A1PDE4B | |
| SCHEMBL13174526 | 0.75 | LMNA (0.38) | LMNAPOLBSMN1; SMN2MMP13MMP3 | |
| SCHEMBL9286227 | 0.75 | SMN1; SMN2 (0.49) | LMNAPOLBSMN1; SMN2MMP13MMP3 | |
| SCHEMBL4470764 | 0.72 | CHRM2 (0.48) | LMNAPOLBSMN1; SMN2CHRM2CHRM1 | |
| SCHEMBL13173647 | 0.71 | LMNA (0.38) | LMNAPOLBSMN1; SMN2CHRM2CHRM1 | |
| SCHEMBL29480883 | 0.70 | LMNA (0.52) | LMNAPOLBSMN1; SMN2MMP13MMP3 | |
| SCHEMBL29480884 | 0.70 | LMNA (0.52) | LMNAPOLBSMN1; SMN2MMP13MMP3 | |
| SCHEMBL6977617 | 0.69 | MEN1 (0.39) | HPGDALDH1A1 | |
| SCHEMBL5186931 | 0.69 | MEN1 (0.39) | HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1542988-A1 | PIPERIDINE QUINOLYL PROPYL DERIVATIVES, PREPARATION METHOD AND INTERMEDIATES AND COMPOSITIONS CONTAINING SAME | Aventis Pharma S.A. (FR) | 2005-06-22 | — | — | EP | disclosed |
| WO-2004024712-A1 | PIPERIDINE QUINOLYL PROPYL DERIVATIVES, PREPARATION METHOD AND INTERMEDIATES AND COMPOSITIONS CONTAINING SAME | AVENTIS PHARMA S.A. (FR) | 2004-03-25 | — | — | WO | disclosed |